Koj puas tau nrhiav txoj hauv kev los txhawb koj txoj kev noj qab haus huv thiab kev noj qab haus huv? Calcium alpha-ketoglutarate cov tshuaj ntxiv yog koj xaiv zoo tshaj.Calcium alpha-ketoglutarate yog qhov sib xyaw ua ke uas ua lub luag haujlwm tseem ceeb hauv lub cev lub zog tsim khoom thiab cov metabolism. Nws kuj yog ib qho tseem ceeb hauv kev tswj cov pob txha kom muaj zog thiab noj qab haus huv, ua rau nws yog ib qho tseem ceeb rau kev noj qab haus huv tag nrho. Los ntawm kev koom nrog calcium alpha ketoglutarate cov tshuaj ntxiv rau hauv koj txoj haujlwm niaj hnub, koj tuaj yeem ntsib ntau yam txiaj ntsig kev noj qab haus huv uas txhim kho koj txoj kev noj qab haus huv.
Ca-AGyog ib qho kev sib xyaw ntawm cov ntxhia calcium thiab alpha-ketoglutarate molecule. Alpha-ketoglutarate yog ib yam khoom tseem ceeb nyob rau hauv lub cev lub zog tsim cov txheej txheem, tshwj xeeb tshaj yog nyob rau hauv lub tricarboxylic acid voj voog, qhov uas nws yog ib qho tseem ceeb rau zus tau tej cov adenosine triphosphate (ATP), lub cev lub ntsiab lub zog.
Tsis tas li ntawd, Ca-AKG ua haujlwm raws li Kreb lub voj voog metabolite thiab α-ketoglutarate yog tsim thaum lub hlwb tawg cov khoom noj khoom haus rau lub zog. Tom qab ntawd nws ntws mus rau hauv thiab nruab nrab ntawm cov hlwb, ua rau muaj ntau yam kev ua neej nyob thiab kev teeb tsa. Nws txawm ua lub luag haujlwm hauv cov noob caj noob ces, ua raws li cov txheej txheem tswj hwm uas tshwm sim los tiv thaiv DNA kev hloov pauv tsis raug uas feem ntau ua rau muaj kab mob xws li mob qog noj ntshav.
Thaum ib tug neeg mus txog ib lub hnub nyoog, lub ntuj theem ntawm α-ketoglutarate hauv lub cev txo qis, thiab qhov kev txo qis no cuam tshuam txog kev laus.
Ntawm lawv, α-ketoglutarate yog α-keto acid uas ua lub luag haujlwm tseem ceeb hauv ntau yam txheej txheem lom neeg. Tsis tas li ntawd, alpha-ketoglutarate kuj yog ib qho tshuaj endogenous, lub ntsiab lus nws yog tsim los ntawm lub cev. Nws tsis tuaj yeem tau txais los ntawm cov khoom noj, tab sis qee qhov kev tshawb fawb qhia tias nws tuaj yeem khaws cia los ntawm kev yoo mov thiab noj ketogenic. Nws zoo nkaus li muaj tsawg kawg yog plaub lub tswv yim tseem ceeb ntawm kev ua. Cov no suav nrog kev tswj hwm cov metabolism hauv kev noj qab haus huv, txhawb kev hloov pauv ntawm cov amino acids tseem ceeb, tiv thaiv DNA thiab tiv thaiv kev mob ntev. Meanwhile, calcium yog ib qho tseem ceeb minerals uas plays lub luag haujlwm tseem ceeb hauv ntau lub cev ua haujlwm, nrog rau cov leeg nqaij, neurotransmission, thiab pob txha noj qab haus huv.
Cov tshuaj Ca-AKG yog kev sib xyaw ua ke ntawm calcium thiab alpha-ketoglutarate uas muaj ntau yam txiaj ntsig, suav nrog kev ua kis las kis las, kev loj hlob ntawm cov leeg, thiab kev txhawb nqa kev noj qab haus huv tag nrho.
Alpha-ketoglutarateyog ib qho molecule uas ua lub luag haujlwm tseem ceeb hauv cellular metabolism. Nws yog ib tug natural compound pom nyob rau hauv lub cev thiab kuj muaj nyob rau hauv kev noj haus ntxiv.
Txhawm rau teb cov lus nug no, nws yog ib qho tseem ceeb kom nkag siab txog cov txheej txheem ntawm kev laus. Kev laus yog cov txheej txheem nyuaj uas muaj ntau yam kev lom neeg thiab ib puag ncig. Ib qho ntawm cov tsav tsheb tseem ceeb ntawm kev laus yog qhov sib txuam ntawm cellular puas thiab ua haujlwm tsis zoo dhau sijhawm. Qhov no tuaj yeem ua rau poob qis hauv kev ua haujlwm ntawm ntau cov ntaub so ntswg thiab cov kabmob, thaum kawg ua rau cov yam ntxwv ntawm kev laus xws li wrinkles, txo qis zog thiab ua rau muaj kab mob ntau ntxiv.
Kev tshawb fawb qhia tias alpha-ketoglutarate tuaj yeem muaj peev xwm thim rov qab qee qhov kev hloov pauv hnub nyoog. Ib txoj kev tshawb fawb luam tawm nyob rau hauv phau ntawv xov xwm Cell Metabolism pom tias ntxiv cov khoom noj ntawm cov nas hnub nyoog nrog alpha-ketoglutarate ua rau muaj txiaj ntsig zoo. Cov no suav nrog kev txhim kho lub cev ua haujlwm, ua kom lub neej ntev, thiab txo cov cim kev laus hauv daim siab thiab cov leeg pob txha.
Cov kws tshawb fawb tseem pom tau tias alpha-ketoglutarate supplementation ua rau muaj kev hloov pauv hauv cov haujlwm ntawm cov noob koom nrog hauv kev tsim hluav taws xob thiab cov metabolism. Qhov no qhia tau hais tias alpha-ketoglutarate tuaj yeem tuaj yeem rov ua cov ntaub so ntswg laus los ntawm kev txhim kho nws lub peev xwm los tsim lub zog thiab kho kev puas tsuaj.
Ntxiv nrog rau nws cov teebmeem ntawm cov metabolism, alpha-ketoglutarate tau pom tias muaj ntau yam txiaj ntsig. Piv txwv li, nws yog ib tug precursor rau zus tau tej cov collagen, ib feem tseem ceeb ntawm daim tawv nqaij thiab lwm yam ntaub so ntswg. Qhov no txhais tau hais tias alpha-ketoglutarate tuaj yeem pab tswj cov qauv thiab kev ua haujlwm ntawm daim tawv nqaij, pab txhawb lub ntsej muag hluas dua.
Calcium yog ib qho tseem ceeb ntxhia uas ua lub luag haujlwm tseem ceeb hauv ntau cov txheej txheem lom neeg hauv lub cev. Ib qho ntawm nws cov haujlwm tsis tshua paub yog nws cov txiaj ntsig ntawm alpha-ketoglutarate, ib feem tseem ceeb ntawm lub voj voog citric acid.
Ua ntej, nws yog ib qho tseem ceeb kom nkag siab tias alpha-ketoglutarate ua dab tsi hauv lub cev. Alpha-ketoglutarate yog ib qho nruab nrab ntawm lub voj voog citric acid (tseem hu ua Krebs cycle) thiab yog lub luag haujlwm rau kev tsim lub zog hauv daim ntawv ntawm adenosine triphosphate (ATP). Lub voj voog no tshwm sim hauv lub cell mitochondria thiab tseem ceeb heev rau cov metabolism ntawm carbohydrates, rog, thiab cov proteins. Alpha-ketoglutarate koom nrog ntau yam tshuaj lom neeg tseem ceeb hauv lub voj voog citric acid, suav nrog kev hloov pauv ntawm isocitrate rau succinyl-CoA.
Kev tshawb fawb qhia tau hais tias calcium ions ua lub luag haujlwm tseem ceeb hauv kev tswj cov haujlwm ntawm cov enzymes koom nrog lub voj voog citric acid, suav nrog cov kev cuam tshuam nrog alpha-ketoglutarate. Tshwj xeeb, calcium ions tswj cov haujlwm ntawm alpha-ketoglutarate dehydrogenase, uas ua rau kev hloov pauv ntawm alpha-ketoglutarate rau succinyl-CoA. Qhov no txhais tau hais tias muaj calcium cuam tshuam tus nqi ntawm α-ketoglutarate metabolism hauv lub voj voog citric acid.
Tsis tas li ntawd, calcium tau pom tias cuam tshuam rau qib alpha-ketoglutarate hauv lub cev. Cov kev tshawb fawb pom tau hais tias kev nce hauv cov calcium hauv cov hlwb ua rau txo qis hauv alpha-ketoglutarate concentrations, thaum txo cov calcium uas muaj qhov cuam tshuam. Qhov no qhia txog txoj kev sib raug zoo ntawm calcium thiab alpha-ketoglutarate, thiab qhov kev hloov pauv ntawm cov calcium uas cuam tshuam rau cov metabolism ntawm cov ntsiab lus tseem ceeb no.
Cov teebmeem ntawm calcium ntawm alpha-ketoglutarate txuas ntxiv dhau lub voj voog citric acid. Alpha-ketoglutarate kuj yog ib qho precursor rau synthesis ntawm glutamate, ib qho tseem ceeb neurotransmitter nyob rau hauv lub hauv paus paj hlwb. Calcium signaling tau pom los tswj cov haujlwm ntawm cov enzymes koom nrog hauv kev tsim cov glutamate los ntawm alpha-ketoglutarate. Qhov no qhia tau hais tias muaj txiaj ntsig zoo ntawm calcium rauα-ketoglutarate metabolism, suav nrog nws lub luag haujlwm hauv kev sib txuas lus neurotransmission.
1.Anti-aging
Ca-AKG tau pom tias muaj peev xwm tiv thaiv kev laus ntawm qib cellular. Ib txoj kev tshawb nrhiav pom tias kev ntxiv nrog Ca-AKG ua rau muaj kev nce hauv cov haujlwm ntawm mitochondria, lub zog ntawm cov hlwb, uas txo qis nrog lub hnub nyoog. Los ntawm kev txhawb nqa mitochondrial muaj nuj nqi, Ca-AKG tuaj yeem pab txhim kho cellular kev noj qab haus huv thiab kev rov zoo, uas yuav muaj txiaj ntsig zoo rau tag nrho lub neej thiab kab mob kev laus.
Tsis tas li ntawd, ib daim ntawv 2019 luam tawm nyob rau hauv phau ntawv xov xwm kev tshuaj xyuas cov neeg laus tau pom tias alpha-ketoglutarate tuaj yeem txuas ntxiv lub neej ntawm nematodes (tseem hu ua roundworms) thiab cov compound tuaj yeem txo cov kev ua ntawm mTOR txoj hauv kev. mTOR inhibition yog txuam nrog ntau yam txiaj ntsig kev noj qab haus huv.Tshwj xeeb, mTOR inhibition tshwm sim los txhawb kev ua haujlwm ntawm tes thiab txo qhov kev pheej hmoo ntawm cov kab mob uas muaj hnub nyoog los ntawm kev nce autophagy.
2.Regulates Zog thiab Metabolism
Ib txoj hauv kev tseem ceeb uas Ca-AKG cuam tshuam rau lub zog thiab cov metabolism yog los ntawm nws lub luag haujlwm hauv lub voj voog citric acid. Lub voj voog no yog lub luag haujlwm rau kev hloov cov khoom noj hauv cov zaub mov, xws li carbohydrates, rog, thiab cov protein, rau hauv adenosine triphosphate (ATP), lub cev lub zog tseem ceeb. Alpha-ketoglutarate yog ib qho tseem ceeb ntawm lub voj voog no vim nws koom nrog ntau yam kev cuam tshuam metabolic. Los ntawm kev muab lub cev nrog lub hauv paus ntawm alpha-ketoglutarate hauv daim ntawv ntawm Ca-AKG, nws tau xav tias tib neeg tuaj yeem txhawb nqa lawv cov txheej txheem tsim hluav taws xob, muaj peev xwm txhim kho tag nrho cov zog thiab cov metabolism.
Tsis tas li ntawd, kev tshawb fawb qhia tias Ca-AKG kuj tseem muaj cov tshuaj antioxidant, uas tuaj yeem txhawb nqa nws lub luag haujlwm ntxiv hauv kev tswj lub zog thiab cov metabolism. Oxidative kev ntxhov siab tshwm sim thaum muaj qhov tsis txaus ntseeg ntawm kev tsim cov dawb radicals thiab lub cev muaj peev xwm tiv thaiv lawv cov teebmeem, thiab txuas nrog ntau yam teeb meem kev noj qab haus huv, suav nrog cov kab mob metabolic. Los ntawm kev ua cov tshuaj antioxidant, Ca-AKG tuaj yeem pab txo qis oxidative kev nyuaj siab, yog li txhawb kom muaj zog ntau lawm thiab cov metabolism.
3. Noj qab haus huv poob phaus thiab tswj
Ca-AKG yog daim ntawv ntsev ntawm alpha-ketoglutarate, ib qho tseem ceeb nruab nrab ntawm lub voj voog citric acid (tseem hu ua Krebs cycle). Lub voj voog no yog qhov tseem ceeb rau kev tsim cov adenosine triphosphate (ATP), peb lub hlwb thawj lub zog. Ntxiv rau nws lub luag haujlwm hauv kev tsim hluav taws xob, alpha-ketoglutarate tseem ua lub luag haujlwm tseem ceeb hauv cov amino acid metabolism.
Qee cov kev tshawb fawb qhia tias Ca-AKG kuj tseem muaj txiaj ntsig zoo rau kev nkag siab ntawm insulin. Insulin yog ib qho tshuaj hormones uas ua lub luag haujlwm tseem ceeb hauv kev tswj cov ntshav qab zib thiab lub zog cia hauv lub cev. Los ntawm kev txhawb nqa insulin rhiab heev, Ca-AKG tuaj yeem pab tib neeg tswj hwm cov ntshav qab zib kom zoo thiab txo qhov kev pheej hmoo ntawm qhov hnyav nce.
Ib txoj kev tshawb fawb tsiaj luam tawm hauv phau ntawv Journal Aging Cell qhia tias alpha-ketoglutarate tuaj yeem txo qhov hnyav thiab txhim kho qee yam rog thiab kab mob. Cov ntsiab lus tseem ceeb suav nrog:
● Cov ntsiab lus muaj roj tsawg
● Txhim kho qabzib kam rau ua
● Nce cov nqaij adipose xim av (rog)
4.Regulates Zog thiab Metabolism
Calcium alpha-ketoglutarate txhim kho lub zog tsim tawm ntawm qib cellular. Los ntawm kev txhawb nqa lub voj voog Krebs, Ca-AKG pab txhim kho kev hloov pauv ntawm cov as-ham rau hauv ATP, peb lub hlwb lub hauv paus ntawm lub zog.
Tsis tas li ntawd, calcium alpha ketoglutarate tau pom tias txhawb kev noj qab haus huv metabolism. Metabolism hais txog cov txheej txheem tshuaj lom neeg lub neej uas tshwm sim hauv peb lub cev, thiab cov metabolism ua haujlwm zoo yog qhov tseem ceeb rau kev tsim hluav taws xob, kev loj hlob, thiab kho. Ca-AKG pab tswj cov metabolism los ntawm kev txhawb nqa kev siv cov carbohydrates, cov rog, thiab cov proteins, lub hlwb lub zog tseem ceeb.
Ntxiv rau nws lub luag haujlwm hauv kev tsim hluav taws xob thiab kev tswj hwm cov metabolism, calcium alpha-ketoglutarate kuj muaj cov khoom antioxidant. Raws li ib qho antioxidant, Ca-AKG pab cuam tshuam cov dawb radicals, uas tuaj yeem ua rau cov hlwb puas thiab ua rau muaj ntau yam mob xws li oxidative kev nyuaj siab, mob, thiab kev laus. Los ntawm kev txo qis oxidative puas tsuaj, calcium alpha-ketoglutarate txhawb nqa tag nrho cov cell noj qab haus huv thiab kev ua haujlwm.
Ib qho tseem ceeb tshaj plaws los xav txog thaum xaiv Ca-AKG ntxiv yog qhov zoo ntawm cov khoom. Tshawb nrhiav cov tshuaj uas tsim los ntawm cov chaw tsim khoom muaj npe nrov uas ua raws li kev tsim khoom zoo (GMP) thiab yog tus thib peb kuaj rau purity thiab potency. Qhov no yuav ua kom koj tau txais cov khoom lag luam zoo uas tsis muaj kab mob thiab ua tau raws li daim ntawv thov.
Lwm qhov kev txiav txim siab tseem ceeb thaum xaiv Ca-AKG ntxiv yog daim ntawv ntxiv. Ca-AKG muaj nyob rau hauv cov hmoov thiab tshuaj ntsiav, txhua tus muaj nws tus kheej zoo thiab qhov tsis zoo. Powdered supplements feem ntau yooj yim dua los ntawm lub cev thiab tuaj yeem muab sib xyaw rau hauv cov dej qab zib los yog smoothies kom yooj yim noj. Capsules, ntawm qhov tod tes, yog qhov yooj yim thiab yooj yim nqa mus ncig. Thaum xaiv daim ntawv ntxiv uas zoo tshaj rau koj, xav txog koj txoj kev ua neej thiab kev nyiam ntawm tus kheej.
Ntxiv nrog rau qhov zoo thiab daim ntawv, nws tseem ceeb heev uas yuav tau xav txog cov koob tshuaj thiab cov concentration ntawm Ca-AKG hauv cov tshuaj ntxiv. Nrhiav cov khoom uas muab cov tshuaj Ca-AKG txaus kom tau raws li koj tus kheej xav tau. Nws tseem yog ib qho tseem ceeb uas yuav tau xav txog qhov concentration ntawm Ca-AKG hauv cov tshuaj ntxiv - qhov siab dua yuav xav tau cov koob tshuaj me me, uas yuav yooj yim dua rau qee tus neeg.
Tsis tas li ntawd, nws yog ib qho tseem ceeb uas yuav tau xav txog lwm yam khoom xyaw hauv Ca-AKG tshuaj. Qee cov tshuaj ntxiv yuav muaj cov tshuaj ntxiv, tshuaj tua kab mob, lossis cov tshuaj ua xua uas koj xav kom zam. Yog tias koj muaj kev ua xua lossis kev txwv kev noj zaub mov, nrhiav cov tshuaj ntxiv nrog cov khoom xyaw me me thiab tsis muaj cov tshuaj ua xua.
Thaum kawg, xav txog tus nqi thiab tus nqi ntawm Ca-AKG supplementation. Txawm hais tias nws yuav ntxias kom xaiv qhov kev xaiv pheej yig tshaj plaws, nws tseem ceeb heev uas yuav tsum xav txog tag nrho cov nqi ntxiv. Nrhiav ib yam khoom uas muaj cov qauv zoo, muaj zog ntawm tus nqi pheej yig. Xav txog tus nqi ib qho kev pab thiab tag nrho cov nqi ntawm cov tshuaj ntxiv raws li nws qhov zoo, daim ntawv, ntau npaum li cas, thiab lwm yam khoom xyaw.
Suzhou Myland Pharm & Nutrition Inc.tau koom nrog kev lag luam khoom noj khoom haus ntxiv txij li xyoo 1992. Nws yog thawj lub tuam txhab hauv Suav teb los tsim thiab ua lag luam txiv hmab txiv ntoo extract.
Nrog 30 xyoo ntawm kev paub thiab tsav los ntawm cov cuab yeej siv siab thiab lub tswv yim zoo R & D, lub tuam txhab tau tsim ntau yam khoom sib tw thiab dhau los ua lub neej tshiab kev tshawb fawb ntxiv, kev cai synthesis thiab tsim cov tuam txhab.
Tsis tas li ntawd, lub tuam txhab tseem yog ib lub chaw tsim khoom lag luam FDA tso npe, ua kom tib neeg noj qab haus huv nrog kev ruaj ntseg zoo thiab kev loj hlob zoo. Lub tuam txhab R & D cov peev txheej thiab cov chaw tsim khoom thiab cov cuab yeej tshuaj ntsuam xyuas yog niaj hnub thiab muaj ntau yam, thiab muaj peev xwm tsim cov tshuaj ntawm ib milligram rau tuj nplai raws li ISO 9001 cov qauv thiab GMP kev tsim khoom.
Q: Calcium Alpha Ketoglutarate yog dab tsi?
A: Calcium Alpha Ketoglutarate yog ib qho ntxiv uas ua ke nrog calcium nrog alpha ketoglutaric acid, uas yog ib qho chaw ua haujlwm tseem ceeb hauv kev tsim hluav taws xob thiab cov khoom noj metabolism hauv lub cev.
Q: Dab tsi yog cov txiaj ntsig ntawm kev noj tshuaj Calcium Alpha Ketoglutarate?
A: Cov tshuaj Calcium Alpha Ketoglutarate tau pom tias pab txhawb cov pob txha noj qab haus huv, txhim kho cov leeg nqaij, txhim kho kev tawm dag zog, thiab txhawb kev noj qab haus huv thiab kev noj qab haus huv.
Q: Cov Calcium Alpha Ketoglutarate puas tuaj yeem pab cov neeg ncaws pob thiab cov neeg nyiam noj qab haus huv?
A: Yog lawm, Calcium Alpha Ketoglutarate cov tshuaj tuaj yeem txhim kho kev tawm dag zog thiab kev ua siab ntev los ntawm kev txhim kho lub zog tsim thiab cov khoom noj metabolism hauv lub cev.
Kev lees paub: Kab lus no yog rau cov ntaub ntawv dav dav nkaus xwb thiab yuav tsum tsis txhob raug txhais raws li cov lus qhia kho mob. Qee cov ntaub ntawv blog tshaj tawm los ntawm Is Taws Nem thiab tsis yog kev tshaj lij. Lub vev xaib no tsuas yog lub luag haujlwm rau kev txheeb xyuas, formatting thiab kho cov ntawv. Lub hom phiaj ntawm kev xa cov ntaub ntawv ntau ntxiv tsis txhais tau hais tias koj pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Nco ntsoov sab laj nrog tus kws kho mob ua ntej siv cov tshuaj ntxiv lossis hloov pauv koj txoj kev kho mob.
Post lub sij hawm: Feb-22-2024
