Thaum nws los txog rau kev tswj hwm txoj kev noj qab haus huv, nws tseem ceeb heev uas yuav tsum xav txog txhua yam ntawm kev noj qab haus huv thiab khoom noj khoom haus. Kev sib koom ua ke ntawm evodiamine ntxiv rau hauv koj txoj kev noj qab haus huv thiab kev noj haus tuaj yeem yog txoj hauv kev zoo los pab txhawb koj txoj kev noj qab haus huv thiab kev noj qab haus huv. Txawm hais tias koj xav tswj koj qhov hnyav, txhawb kev zom zaub mov noj qab haus huv, lossis txhawb kev ua haujlwm ntawm lub plawv, evodiamine tuaj yeem pab. Evodiamine yog ib yam khoom ntuj tsim nyob rau hauv cov txiv hmab txiv ntoo ntawm tsob ntoo Evodia. Nws tau siv rau hauv cov tshuaj suav tshuaj rau ntau pua xyoo thiab paub txog nws cov txiaj ntsig kev noj qab haus huv.
Evodiamine yog cais raws li bioactive alkaloid thiab pom nyob rau hauv cov txiv hmab txiv ntoo ntawm Evodiamine cog. Qhov no txhais tau tias nws muaj peev xwm cuam tshuam nrog ntau yam txheej txheem lom neeg hauv lub cev. Qhov sib xyaw no tau kawm txog nws cov txiaj ntsig zoo ntawm cov metabolism, tswj qhov hnyav, thiab kev noj qab haus huv tag nrho. Hauv cov tshuaj suav tshuaj, evodiamine yog siv los txhawb kev zom zaub mov, txo qhov mob, thiab txhawb zog sib npaug. Hauv kev tshawb fawb niaj hnub no, evodiamine tau kawm txog nws lub peev xwm los ua thermogenic, txhais tau tias nws yuav muaj peev xwm ua kom lub cev tsim hluav taws xob thiab siv hluav taws xob.
Qee cov kev tshawb fawb qhia tias evodiamine tuaj yeem muaj peev xwm ua kom lub cev metabolic nce ntxiv, ua rau muaj calorie ntau dua thiab muaj peev xwm poob phaus. Tsis tas li ntawd, evodiamine tau kawm txog nws lub peev xwm los txhawb cov xim ntawm cov nqaij dawb adipose, uas tuaj yeem cuam tshuam rau kev txhim kho cov metabolism hauv kev noj qab haus huv thiab txo cov kev pheej hmoo ntawm kev rog rog.
Nws paub tias qhov mob thiab oxidative kev nyuaj siab ua lub luag haujlwm hauv kev txhim kho ntawm ntau yam kab mob, yog li cov tebchaw muaj peev xwm tiv thaiv cov txheej txheem no yog qhov txaus siab rau cov kws tshawb fawb thiab cov kws kho mob. Qee qhov kev tshawb fawb qhia tias evodiamine tuaj yeem muaj peev xwm txo tau qhov mob thiab tiv thaiv oxidative puas tsuaj, uas yuav cuam tshuam rau kev txhawb nqa tag nrho kev noj qab haus huv thiab kev noj qab haus huv.
Tam sim no, evodiamine feem ntau muaj nyob rau hauv kev noj haus ntxiv, uas muaj cov txiaj ntsig kev noj qab haus huv rau tib neeg lub cev.
Evodiamine tau pom tias siv nws cov teebmeem los ntawm ntau txoj hauv kev molecular. Ib qho ntawm cov txheej txheem tseem ceeb ntawm kev ua ntawm evodiamine yog nws lub peev xwm los ua kom muaj peev xwm ua kom muaj peev xwm hloov pauv hloov mus rau vanilloid 1 (TRPV1) channels. TRPV1 yog ib qho receptor cuam tshuam rau qhov mob thiab qhov kub thiab txias, thiab ua kom nws los ntawm evodiamine tau pom tias yuav ua rau cov thermogenesis thiab nce kev siv hluav taws xob. Qhov no thermogenic nyhuv ntawm evodiamine tuaj yeem pab txhawb rau nws cov khoom tiv thaiv kev rog, ua rau nws lub hom phiaj rau kev txhim kho kev poob phaus.
Ntxiv rau nws cov teebmeem ntawm TRPV1, evodiamine tau pom los hloov lwm lub hom phiaj molecular, suav nrog adenosine monophosphate-activated protein kinase (AMPK) thiab peroxisome proliferator-activated receptor gamma (PPARγ). AMPK yog tus tswj hwm tseem ceeb ntawm cellular zog homeostasis, thiab nws qhov kev ua haujlwm los ntawm evodiamine txhawb nqa cov piam thaj thiab fatty acid oxidation, yog li txhim kho insulin rhiab heev thiab kev noj qab haus huv metabolic. Ntawm qhov tod tes, ua kom PPARγ los ntawm evodiamine tuaj yeem tswj cov kev qhia ntawm cov noob koom nrog hauv lipid metabolism thiab adipogenesis, ntxiv rau nws cov kev tiv thaiv kev rog.
Tsis tas li ntawd, evodiamine tau pom tias muaj cov tshuaj tiv thaiv kab mob los ntawm inhibiting nuclear factor kappa B (NF-κB) signaling. NF-κB yog lub hauv paus tswj hwm ntawm inflammatory teb, thiab nws cov dysregulation yog txuam nrog ntau yam mob inflammatory kab mob. Los ntawm inhibiting NF-κB ua kom, evodiamine tuaj yeem txo qis kev tsim cov tshuaj tiv thaiv kab mob thiab txo cov txheej txheem inflammatory, qhia txog nws lub luag haujlwm kho mob hauv kev kho cov kab mob inflammatory.
Tsis tas li ntawd, cov tshuaj tiv thaiv kab mob qog noj ntshav ntawm evodiamine raug ntaus nqi rau nws lub peev xwm los ua kom apoptosis thiab inhibit kev loj hlob ntawm ntau yam kab mob qog noj ntshav. Qhov no tau xav tias yuav tshwm sim los ntawm kev tswj hwm ntawm ntau txoj hauv kev qhia txog kev muaj sia nyob ntawm tes thiab kev loj hlob, suav nrog mitogen-activated protein kinase (MAPK) thiab phosphoinositide 3-kinase (PI3K) / Akt pathways. Tsis tas li ntawd, evodiamine tau pom tias inhibit qhov kev qhia ntawm matrix metalloproteinases (MMPs), enzymes koom nrog hauv qog nqaij hlav thiab metastasis.
1. Pab nrog poob phaus thiab txo cov metabolism
Tus yuam sij rau evodiamine pab nrog kev poob phaus yog nce thermogenesis hauv lub cev. Thermogenesis yog cov txheej txheem uas lub cev ua kom sov thiab hlawv calories. Los ntawm stimulating thermogenesis, evodiamine tuaj yeem pab txhawb cov metabolism thiab txhawb kev rog rog. Qhov no txhais tau tias koj hlawv ntau calorie ntau ntau nyob rau ib hnub, txawm tias thaum so, ua rau kom poob phaus ntxiv rau lub sijhawm.
Ntxiv nrog rau nws cov teebmeem ntawm thermogenesis, evodiamine kuj tseem muaj cov teebmeem ntawm cov roj metabolism. Kev tshawb fawb qhia tau hais tias evodiamine tuaj yeem pab ua kom tawg ntawm cov rog thiab inhibit tsim cov rog tshiab. Qhov no txhais tau hais tias tsis yog nws pab koj hlawv cov khw muag khoom rog uas twb muaj lawm, nws tseem tiv thaiv kev sib sau ntawm cov rog tshiab, ua rau nws yooj yim dua los tswj qhov hnyav hauv lub sijhawm ntev.
Tsis tas li ntawd, evodiamine tau pom tias muaj peev xwm ua kom qab los noj mov. Los ntawm kev txo cov kev tshaib kev nqhis thiab ua kom muaj kev xav puv, evodiamine tuaj yeem pab koj noj tsawg calories, ua kom yooj yim rau koj cov zaub mov thiab ua tiav koj cov hom phiaj poob phaus. Tsis tas li ntawd, qee qhov kev tshawb fawb qhia tias evodiamine kuj tseem muaj cov tshuaj tiv thaiv kab mob thiab antioxidant, uas yuav pab tau tag nrho kev noj qab haus huv thiab kev noj qab haus huv thaum poob phaus.
2. Pab txo qhov mob
Evodiamine yog muab los ntawm cov txiv hmab txiv ntoo ntawm Evodia rutaecarpa tsob nroj, uas tau siv rau hauv cov tshuaj suav tshuaj los kho ntau yam mob rau ntau pua xyoo. Kev tshawb fawb ntawm evodiamine qhia tau hais tias nws inhibits zus tau tej cov inflammatory molecules nyob rau hauv lub cev, xws li cytokines thiab prostaglandins. Qhov no pab txo qis tag nrho cov kab mob hauv lub cev, yog li txo qhov mob thiab lwm yam tsos mob cuam tshuam nrog kev mob ntev.
Ib txoj kev tshawb fawb luam tawm nyob rau hauv phau ntawv Journal of Ethnopharmacology pom tias evodiamine muaj cov tshuaj tiv thaiv kab mob tseem ceeb hauv cov nas uas ua rau mob. Cov kws tshawb fawb tau xaus lus tias evodiamine yuav yog ib qho kev kho mob zoo rau cov kab mob inflammatory. Lwm txoj kev tshawb fawb hauv phau ntawv Journal Phytomedicine tau pom tias evodiamine muaj cov tshuaj tiv thaiv kab mob hauv cov kab lis kev cai ntawm tes, qhia tias nws kuj yog ib qho kev kho mob zoo rau tib neeg.
3. Pab cov hlab plawv
Evodiamine tau pom tias muaj vasodilatory zog, uas txhais tau tias nws tuaj yeem pab so thiab nthuav cov hlab ntsha, yog li txhim kho cov ntshav txaus. Qhov no yog qhov tshwj xeeb tshaj yog rau cov neeg uas muaj ntshav siab, vim nws tuaj yeem pab txo qis kev ua haujlwm ntawm lub plawv thiab txo qhov kev pheej hmoo ntawm cov teeb meem xws li mob stroke lossis plawv nres.
Tsis tas li ntawd, evodiamine tau kawm txog nws lub peev xwm los txo qhov mob thiab oxidative kev nyuaj siab, ob qho tib si muaj feem cuam tshuam nrog kev loj hlob ntawm cov kab mob plawv. Los ntawm kev txo cov kev pheej hmoo no, evodiamine tuaj yeem pab tiv thaiv lub plawv thiab cov hlab ntsha ntawm kev puas tsuaj thiab ua haujlwm tsis zoo. Evodiamine tau pom tias muaj cov nyhuv antiplatelet thiab antithrombotic, txhais tau tias nws tuaj yeem pab tiv thaiv cov ntshav txhaws los ntawm kev tsim. Cov ntshav txhaws tuaj yeem cuam tshuam cov ntshav ntws thiab ua rau cov hlab plawv mob hnyav, yog li evodiamine lub peev xwm los tiv thaiv cov ntshav txhaws tuaj yeem cuam tshuam rau cov hlab plawv.
4. Txhawb nqa kev noj qab haus huv ntawm plab hnyuv
Kev tshawb fawb qhia tias evodiamine tuaj yeem muaj ntau yam txiaj ntsig zoo rau lub plab zom mov. Nws muaj anti-inflammatory thiab antioxidant zog uas pab tiv thaiv lub plab thiab plab hnyuv kab mob los ntawm kev puas tsuaj los ntawm dawb radicals thiab o. Tsis tas li ntawd, evodiamine tau pom tias muaj cov tshuaj tua kab mob thiab tuaj yeem pab txhawb kev noj qab haus huv ntawm cov kab mob hauv plab thiab txo qis kev pheej hmoo ntawm kab mob plab.
Tsis tas li ntawd, evodiamine tau pom tias muaj cov khoom tiv thaiv kab mob, pab txo qis kev pheej hmoo ntawm plab rwj thiab lwm yam kab mob hauv plab. Los ntawm kev txhawb nqa kev ncaj ncees ntawm cov mucosal hauv ob sab phlu thiab inhibiting acid secretion, evodiamine tuaj yeem pab tiv thaiv lub plab thiab cov hnyuv los ntawm kev puas tsuaj thiab khaus.
5.Lwm cov txiaj ntsig kev noj qab haus huv
Evodiamine muaj peev xwm tswj cov ntshav qab zib. Cov ntshav qab zib ntau tuaj yeem ua rau muaj ntau yam teeb meem kev noj qab haus huv, suav nrog ntshav qab zib thiab kab mob plawv. Kev tshawb fawb qhia tau hais tias evodiamine tuaj yeem pab txhim kho insulin rhiab heev thiab tswj cov ntshav qab zib, ua rau nws yog ib qho cuab yeej tseem ceeb rau txhua tus neeg saib xyuas cov ntshav qab zib kom noj qab haus huv.
Ntxiv nrog rau nws lub peev xwm los tswj cov ntshav qab zib, evodiamine kuj tau pom tias txo qis cov roj cholesterol. Cov qib roj cholesterol siab ua rau koj txoj kev pheej hmoo ntawm kab mob plawv thiab mob stroke, yog li nrhiav txoj hauv kev los txo koj cov qib roj cholesterol yog qhov tseem ceeb rau kev tswj hwm koj txoj kev noj qab haus huv tag nrho. Evodiamine tau pom tias txo qis LDL cov roj (cholesterol) phem thaum nce qib HDL cholesterol (tseem hu ua "zoo" cholesterol).
Tsis tas li ntawd, evodiamine tau pom los ua kom muaj zog tag nrho. Hauv lub ntiaj teb niaj hnub no, ntau tus neeg tawm tsam nrog lub zog qis thiab qaug zog. Evodiamine tau pom tias yuav ua rau kom cov metabolism thiab kev siv hluav taws xob, yog li ib txwm txhawb nqa qib zog. Qhov no tshwj xeeb tshaj yog muaj txiaj ntsig zoo rau cov neeg ncaws pob lossis txhua tus neeg uas xav txhim kho lawv lub zog thiab lub zog tag nrho.
Thaum sib piv cov tshuaj evodiamine, thawj qhov yuav tsum tau xav txog yog lub hauv paus ntawm evodiamine. Nws yog ib qho tseem ceeb uas yuav tau xaiv ib qho ntxiv uas siv cov khoom zoo, ntshiab evodiamine extract los ntawm lub npe nrov. Nrhiav cov khoom uas yog tus neeg thib peb kuaj thiab muaj daim ntawv pov thawj ntawm kev soj ntsuam kom paub meej purity thiab potency.
Lwm qhov tseem ceeb uas yuav tau xav txog yog qhov ntau npaum li cas ntawm evodiamine hauv cov tshuaj ntxiv. Cov koob tshuaj evodiamine tau pom zoo yuav txawv nyob ntawm tus neeg thiab lawv cov hom phiaj kev noj qab haus huv. Qee cov tshuaj yuav muaj ntau dua lossis qis dua ntawm evodiamine, yog li nws tseem ceeb heev uas yuav tau xaiv ib qho uas ua tau raws li koj xav tau thiab nyiam.
Ntxiv rau cov ntsiab lus evodiamine, nws tseem ceeb heev uas yuav tau xav txog lwm cov khoom xyaw hauv koj cov tshuaj ntxiv. Qee cov tshuaj evodiamine yuav muaj lwm cov khoom xyaw, xws li kua txob dub los yog ntsuab tshuaj yej extract.
Tsis tas li ntawd, daim ntawv ntawm cov tshuaj ntxiv yog lwm qhov tseem ceeb rau kev txiav txim siab. Cov tshuaj Evodiamine muaj nyob rau hauv ntau hom, suav nrog tshuaj ntsiav, hmoov, thiab tinctures. Xaiv ib hom ntawv uas yooj yim thiab yooj yim los muab tso rau hauv koj lub neej txhua hnub. Piv txwv li, yog tias koj muaj teeb meem nqos cov ntsiav tshuaj, hmoov yuav yog qhov kev xaiv zoo dua rau koj.
Nws tseem ceeb heev uas yuav tau xav txog qhov zoo thaum xaiv ib qho evodiamine ntxiv. Saib rau cov chaw tsim khoom pej xeem nrog keeb kwm ntawm kev tsim cov tshuaj zoo thiab cov neeg siv khoom zoo. Tshawb nrhiav cov txheej txheem tsim khoom lag luam thiab kev tswj xyuas kom zoo kom ntseeg tau tias koj tau txais cov khoom lag luam muaj kev nyab xeeb thiab txhim khu kev qha.
Thaum kawg, thaum xaiv ib qho evodiamine ntxiv, xav txog koj tus kheej lub hom phiaj kev noj qab haus huv thiab txhua yam kev txhawj xeeb txog kev noj qab haus huv. Qee tus neeg yuav xav tau evodiamine rau kev tswj qhov hnyav, thaum lwm tus yuav xav txhawb kev noj qab haus huv lossis kev noj qab haus huv tag nrho. Tsis tas li ntawd, sab laj nrog kws kho mob ua ntej pib cov txheej txheem ntxiv tshiab, tshwj xeeb tshaj yog tias koj muaj mob uas twb muaj lawm lossis noj tshuaj.
Suzhou Myland Pharm & Nutrition Inc. tau koom nrog kev lag luam khoom noj khoom haus ntxiv txij li xyoo 1992. Nws yog thawj lub tuam txhab hauv Suav teb los tsim thiab ua lag luam txiv hmab txiv ntoo extract.
Nrog 30 xyoo ntawm kev paub thiab tsav los ntawm cov cuab yeej siv siab thiab lub tswv yim zoo R & D, lub tuam txhab tau tsim ntau yam khoom sib tw thiab dhau los ua lub neej tshiab kev tshawb fawb ntxiv, kev cai synthesis thiab tsim cov tuam txhab.
Tsis tas li ntawd, lub tuam txhab tseem yog ib lub chaw tsim khoom lag luam FDA tso npe, ua kom tib neeg noj qab haus huv nrog kev ruaj ntseg zoo thiab kev loj hlob zoo. Lub tuam txhab R & D cov peev txheej thiab cov chaw tsim khoom thiab cov cuab yeej tshuaj ntsuam xyuas yog niaj hnub thiab muaj ntau yam, thiab muaj peev xwm tsim cov tshuaj ntawm ib milligram rau tuj nplai raws li ISO 9001 cov qauv thiab GMP kev tsim khoom.
Q: Evodiamine yog dab tsi?
A: Evodiamine yog lub ntuj tsim muaj nyob hauv cov txiv hmab txiv ntoo ntawm Evodia rutaecarpa tsob nroj, Nws tau siv rau hauv cov tshuaj suav tshuaj rau ntau pua xyoo thiab paub txog nws cov txiaj ntsig kev noj qab haus huv.
Q: Dab tsi yog cov txiaj ntsig zoo ntawm cov tshuaj evodiamine?
A: Cov tshuaj Evodiamine ntseeg tau tias muaj ntau yam txiaj ntsig kev noj qab haus huv, suav nrog kev txhawb nqa kev tswj hwm qhov hnyav, metabolism, thiab kev noj qab haus huv tag nrho. Tsis tas li ntawd, lawv tuaj yeem muaj cov tshuaj tiv thaiv kab mob thiab antioxidant.
Q: Kuv yuav tsum muab cov tshuaj evodiamine rau hauv kuv txoj kev noj qab haus huv thiab kev noj haus li cas?
A: Ua ntej muab cov tshuaj ntxiv rau hauv koj txoj kev noj qab haus huv thiab kev noj haus, nws yog ib qho tseem ceeb uas yuav tau sab laj nrog tus kws kho mob. Lawv tuaj yeem pab koj txiav txim siab npaum li cas thiab ntsuas qhov muaj peev xwm cuam tshuam nrog lwm cov tshuaj lossis tshuaj ntxiv uas koj yuav tau noj.
Q: Puas muaj tej yam kev mob tshwm sim ntawm cov tshuaj evodiamine?
A: Thaum cov tshuaj evodiamine feem ntau suav hais tias muaj kev nyab xeeb rau tib neeg feem ntau thaum noj cov tshuaj kom tsim nyog, qee tus neeg yuav muaj kev phiv xws li plab zom mov lossis khaus khaus. Nws yog ib qho tseem ceeb uas yuav tau ua raws li cov lus pom zoo thiab saib xyuas koj lub cev cov lus teb rau cov tshuaj ntxiv.
Q: Puas muaj kev ceev faj los xav txog thaum noj tshuaj evodiamine?
A: Yog tias koj cev xeeb tub, laus, lossis muaj mob hauv qab no, nws yog ib qho tseem ceeb uas yuav tau tham nrog tus kws kho mob ua ntej noj cov tshuaj evodiamine. Tsis tas li ntawd, nws yog ib qho tseem ceeb uas yuav tau yuav cov khoom ntxiv los ntawm qhov chaw muaj koob npe los ua kom zoo thiab kev nyab xeeb.
Kev lees paub: Kab lus no yog rau cov ntaub ntawv dav dav nkaus xwb thiab yuav tsum tsis txhob raug txhais raws li cov lus qhia kho mob. Qee cov ntaub ntawv blog tshaj tawm los ntawm Is Taws Nem thiab tsis yog kev tshaj lij. Lub vev xaib no tsuas yog lub luag haujlwm rau kev txheeb xyuas, formatting thiab kho cov ntawv. Lub hom phiaj ntawm kev xa cov ntaub ntawv ntau ntxiv tsis txhais tau hais tias koj pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Nco ntsoov sab laj nrog tus kws kho mob ua ntej siv cov tshuaj ntxiv lossis hloov pauv koj txoj kev kho mob.
Post lub sij hawm: Feb-02-2024
