Kev noj haus ntxiv-Cov khoom tshiab rau kev ua neej ntev thiab tiv thaiv kev laus: Calcium Alpha-ketoglutarate

Calcium Alpha ketoglutarate (AKG) yog ib qho metabolite nruab nrab ntawm lub voj voog tricarboxylic acid thiab koom nrog kev tsim cov amino acids, vitamins, thiab cov organic acids thiab kev ua kom lub zog metabolism. Nws tuaj yeem siv ua cov khoom noj khoom haus ntxiv thiab muaj kev cia siab dav dav. Ntxiv rau nws cov haujlwm biological hauv tib neeg lub cev, calcium alpha-ketoglutarate kuj tseem siv dav hauv kev lag luam tshuaj thiab tau dhau los ua ib qho tseem ceeb ntawm ntau cov khoom noj khoom haus thiab kev daws teeb meem kho mob.

Yuav ua li cas calcium alpha-ketoglutarate ua haujlwm

Ua ntej,calpha-ketoglutarate alpha-ketoglutarateua lub luag haujlwm tseem ceeb hauv kev hloov pauv lub zog. Raws li cov khoom nruab nrab ntawm lub voj voog tricarboxylic acid (TCA voj voog), calcium α-ketoglutarate koom nrog hauv cov txheej txheem tsim lub zog hauv lub hlwb. Los ntawm lub voj voog TCA, cov as-ham xws li carbohydrates, rog, thiab cov protein raug oxidized thiab decomposed los tsim ATP (adenosine triphosphate) los muab lub zog rau cov hlwb. Raws li cov khoom nruab nrab tseem ceeb hauv lub voj voog TCA, calcium α-ketoglutarate tuaj yeem txhawb kev hloov pauv lub zog ntawm lub hlwb, ua rau lub cev muaj zog ntau dua, pab txhim kho lub zog thiab kev ua siab ntev, thiab txhim kho kev qaug zog ntawm lub cev.

Qhov thib ob, calcium α-ketoglutarate ua lub luag haujlwm tseem ceeb hauv kev hloov pauv amino acid. Amino acids yog cov khoom tseem ceeb ntawm cov protein, thiab calcium α-ketoglutarate koom nrog kev hloov pauv thiab kev hloov pauv ntawm amino acids. Hauv cov txheej txheem ntawm kev hloov pauv amino acids mus rau lwm cov metabolites, calcium α-ketoglutarate transaminates nrog amino acids los tsim cov amino acids tshiab lossis α-keto acids, yog li tswj kev sib npaug thiab kev siv cov amino acids. Tsis tas li ntawd, calcium α-ketoglutarate kuj tseem tuaj yeem ua haujlwm ua lub substrate oxidation rau amino acids, koom nrog hauv kev hloov pauv oxidative ntawm amino acids, thiab tsim lub zog thiab carbon dioxide. Yog li ntawd, calcium α-ketoglutarate yog qhov tseem ceeb heev hauv kev tswj hwm homeostasis ntawm amino acids thiab protein metabolism hauv lub cev.

Ntxiv rau, calcium alpha-ketoglutarate ua haujlwm ua cov tshuaj antioxidant uas tshem tawm cov free radicals thiab tiv thaiv cov cell ntawm kev puas tsuaj oxidative. Tib lub sijhawm, calcium α-ketoglutarate kuj tseem tuaj yeem tswj hwm kev ua haujlwm ntawm lub cev tiv thaiv kab mob, txhawb kev ua haujlwm thiab kev loj hlob ntawm cov cell tiv thaiv kab mob, thiab txhim kho lub cev tiv thaiv kab mob thiab kev kis kab mob. Yog li ntawd, calcium α-ketoglutarate yog qhov tseem ceeb heev hauv kev tswj lub cev tiv thaiv kab mob thiab tiv thaiv kab mob.

Kev tshawb fawb txog cov teebmeem ntawm kev laus

Kev laus zuj zus cuam tshuam rau peb txhua tus thiab yog ib qho ua rau muaj ntau yam kab mob, thiab raws li cov ntaub ntawv hais txog kev lag luam Medicare, qhov muaj feem yuav muaj kab mob nce ntxiv thaum muaj hnub nyoog. Yuav kom txo tau kev laus thiab txo qhov kev pheej hmoo ntawm kab mob, kev tshawb fawb tau tshawb pom ib yam khoom muaj kev nyab xeeb thiab muaj txiaj ntsig zoo uas tuaj yeem cuam tshuam rau kev laus - calcium alpha-ketoglutarate.

Calcium alpha-ketoglutarate yog ib qho tseem ceeb metabolite hauv peb lub cev, paub txog lub luag haujlwm ntawm lub cell hauv lub voj voog Krebs, lub voj voog tseem ceeb rau kev oxidation ntawm fatty acids thiab amino acids, tso cai rau mitochondria tsim ATP (ATP yog lub zog ntawm cov cell).

Qhov no cuam tshuam nrog kev thauj cov txheej txheem calcium alpha-ketoglutarate, yog li calcium alpha-ketoglutarate kuj tseem tuaj yeem hloov mus ua glutamate thiab tom qab ntawd mus rau hauv glutamine, uas tuaj yeem pab txhawb kev tsim cov protein thiab collagen (collagen yog Ib qho fibrous protein uas ua rau 1/3 ntawm tag nrho cov protein hauv lub cev thiab pab txhawb kev noj qab haus huv ntawm pob txha, tawv nqaij thiab cov leeg nqaij).

Ponce De Leon Health, Inc., ib lub tuam txhab tshawb fawb txog kev ua neej ntev uas tsom mus rau kev hloov pauv kev laus ntawm cov noob caj noob ces, tau ua kev tshawb fawb ntau xyoo ntawm calcium alpha-ketoglutarate rau cov nas hnub nyoog nruab nrab thiab pom tias lub neej ntawm cov nas hauv pawg sim tau nce 12%. Qhov tseem ceeb tshaj, qhov tseem ceeb tshaj plaws, kev tsis muaj zog tau txo qis 46% thiab lub neej noj qab haus huv tau nce 41%. Cov pov thawj qhia tau tias kev noj alpha-ketoglutarate tsis yog tsuas yog ua rau lub neej ntev xwb tab sis kuj ua rau lub neej noj qab haus huv ntev dua.

Calcium α-ketoglutarate, ua ib yam khoom noj khoom haus ntau yam, muaj kev siv dav hauv cov khoom kho mob. Nws muaj ntau yam haujlwm xws li antioxidant, tiv thaiv kev laus, tswj kev tiv thaiv kab mob thiab amino acid metabolism ua rau nws yog ib qho cuab yeej muaj zog los txhim kho tib neeg kev noj qab haus huv. Nrog rau kev paub ntau ntxiv txog kev kho mob thiab kev tshawb fawb tob zuj zus, nws ntseeg tias kev siv α-ketoglutarate calcium hauv kev kho mob yuav tau txais kev saib xyuas thiab kev txhim kho ntau dua.