Tshaj tawm qhov Tseeb Trends hauv Alpha GPC Ntxiv rau 2024

Choline Alfoscerate,tseem hu ua Alpha-GPC, yog ib yam khoom muab rho tawm los ntawm cov nroj tsuag lecithin, tab sis nws tsis yog phospholipid, tab sis phospholipid muab tau los ntawm lipophilic fatty acids. Alpha-GPC yog cov khoom noj muaj txiaj ntsig uas pom muaj nyob hauv txhua lub hlwb ntawm cov tsiaj. Vim tias nws yog hydrophilic heev, nws yog absorbed sai sai tom qab noj qhov ncauj. GPC yog qhov ua ntej ntawm acetylcholine (ACh) thiab tuav cov lus cog tseg zoo hauv choline tsis ua haujlwm.

GPC nkag mus hla cov ntshav-hlwb teeb meem thiab muab ib qhov chaw ntawm choline rau biosynthesis ntawm ACh thiab phosphatidylcholine. Phospholipids thiab acetylcholine, thaum ua tiav ntawm qhov kev pom zoo, txhawb kev paub, kev xav thiab kev noj qab haus huv. Tsis tas li ntawd, qhov sib npaug ntawm Alpha-GPC thiab Ach tuaj yeem txhawb nqa cov txheej txheem physiological thiab txhim kho lub cev kev ua haujlwm. ACh koom nrog cov leeg nqaij thiab yog lub ntsiab lus neurotransmitter uas tswj cov lus teb ntawm lub cev rau kev tawm dag zog.

Txij li thaum tag nrho cov leeg nqaij muaj feem xyuam nrog kev sib cog lus, thiab kev cog lus muaj feem xyuam nrog cov cellular ACH concentration, ua kom ACH ntau ntau optimizes cov leeg nqaij. Piv nrog rau lwm yam choline precursors, Alpha-GPC muaj kev nyab xeeb thiab ua tau zoo nce qib choline hauv cov ntshav thiab lub hlwb. Ntau cov kev tshawb fawb tau lees paub ntau yam txiaj ntsig ntawm Alpha-GPC thiab qhia tias kev noj qab haus huv ntawm qhov ncauj tuaj yeem ua lub luag haujlwm tseem ceeb hauv kev txhim kho cov paj hlwb, kev ua haujlwm ntawm lub cev, thiab txhim kho kev nco.

Kev ua tau zoo ntawm Alpha-GPC

Txhim khu lub hlwb

Cov paj hlwb ntau dua nyob rau hauv lub hlwb, lawv lub zog loj dua, lawv kis tau cov paj hlwb sai dua, thiab lub hlwb muaj zog ua haujlwm ntau dua. Alpha-GPC tuaj yeem txhim kho lub hlwb ua haujlwm los ntawm kev txhim kho qhov tseem ceeb ntawm cov paj hlwb thiab kev muaj peev xwm kis tau ntawm cov paj hlwb. Nyob rau hauv cov nqe lus ntawm kev txhim kho cholinergic neurotransmission, teeb liab kis tau tus mob ntawm paj hlwb cia siab rau kev sib kis ntawm neurotransmitters, thiab acetylcholine yog ib tug tseem ceeb tshuaj xa xov thiab neurotransmitter uas ua kom muaj kev xav thiab tswj kev sib koom tes ntawm lub hlwb thiab tag nrho lub cev. Alpha-GPC tuaj yeem decomposed rau hauv 3-glycerol phosphate thiab choline hauv lub hlwb thiab yog cov khoom siv tau zoo tshaj plaws ntawm acetylcholine. Nws tuaj yeem txhim kho kev nco thiab txhim kho kev xav los ntawm kev txhawb nqa cov synthesis thiab tso tawm ntawm acetylcholine hauv lub hlwb. Nyob rau hauv cov nqe lus ntawm kev txhim kho cov stability thiab fluidity ntawm cell membranes, Alpha-GPC yuav txhawb lub synthesis ntawm phosphoinositide, yog li txhim kho cov stability thiab fluidity ntawm cell membranes. Neurons nrog cov qauv ua tiav tuaj yeem xa cov ntaub ntawv zoo dua thiab txhim kho lub cev kev xav agility. Siv.

Tiv thaiv cov hlab ntsha

Kev loj hlob ntawm cov paj hlwb, uas yog cov yam ntxwv neurotrophic, tuaj yeem tswj cov qia cell sib txawv thiab txhawb kev tsim cov kev sib txuas ntawm neural tshiab. Alpha-GPC tuaj yeem txhawb nqa kev zais ntawm ntau yam neurotrophic yam thiab ua kom muaj kev cuam tshuam txog kev muaj sia nyob ntawm tes, yog li ua rau muaj kev tiv thaiv neuroprotective. Txhim kho lub cev kev txawj ntse. Nyob rau tib lub sijhawm, Alpha-GPC tseem tuaj yeem txhawb nqa qhov tso tawm ntawm cov tshuaj hormones loj hlob thiab tswj lub cev kev noj qab haus huv los ntawm kev ua kom lub cev loj hlob cov tshuaj hormones.

Antioxidant

Oxidation thiab o yog lub ntsiab ua rau lub hlwb hlwb laus thiab tuag. Alpha-GPC tuaj yeem tshem tawm cov dawb radicals hauv lub cev, tawm tsam oxidative kev nyuaj siab, thiab tseem tuaj yeem txo qhov mob xws li nuclear factor NF-κB, qog necrosis factor TNF-α, thiab interleukin IL-6. Qhov kev tso tawm ntawm yam cuam tshuam lub hlwb o, yog li cuam tshuam qhov poob ntawm kev paub txog kev ua haujlwm thiab tiv thaiv qhov tshwm sim thiab kev loj hlob ntawm cov kab mob neurodegenerative. Cov teebmeem cuam tshuam tau raug txhawb los ntawm kev kho mob.

Nyob rau hauv txoj kev tshawb no "Cov nyhuv ntawm Alpha-GPC ntawm lub hnub nyoog-Related Memory Impairment", 4 cov kev kawm tau muab placebo, thiab lwm yam 5 cov kev kawm tau muab Alpha-GPC (1200 mg / hnub), tom qab kev tswj qhov ncauj tas li rau 3 lub hlis, 16. Cov electrodes tau siv los sau cov hlwb nthwv dej rau 5 feeb thaum cov ntsiab lus tsaug zog thiab so. Cov txiaj ntsig tau pom tias piv nrog cov placebo, Alpha-GPC muaj peev xwm ua kom muaj qhov sib npaug ntawm lub hlwb nrawm tshaj plaws, thaum muaj kev xav txo qis qis tshaj plaws. Ntawd yog, nws tuaj yeem txhim kho lub hlwb tseem ceeb ntawm cov neeg laus nruab nrab thiab ncua kev laus ntawm lub cev.

Tswj kev xav

Dopamine tuaj yeem ua rau tib neeg zoo siab, thiab serotonin thiab gamma-aminobutyric acid tuaj yeem tswj lub cev lub siab. Alpha-GPC tuaj yeem txhawb kev tso tawm ntawm dopamine, nce-tswj cov kev qhia ntawm dopamine transporters, txhim kho dopamine neurotransmission hauv lub hlwb, thiab nce qib ntawm serotonin hauv striatum thiab prefrontal cortex; Nws tseem tuaj yeem txhawb nqa γ- Kev tso tawm ntawm aminobutyric acid relieves insomnia, yog li exerting nws anti-depressant, ntxhov siab vim-relieving thiab mus ob peb vas-stabilizing teebmeem.

Tsis tas li ntawd, Alpha-GPC kuj zoo nkaus li tuaj yeem txhim kho qhov nqus ntawm cov hlau tsis muaj hlau hauv cov khoom noj, zoo ib yam li cov txiaj ntsig ntawm vitamin C ntawm 2: 1 piv nrog hlau, yog li Alpha-GPC raug suav hais tias yog, lossis ntawm tsawg pab txhawb rau, txhim kho cov khoom noj nqaij. Phenomenon ntawm nonheme hlau nqus. Tsis tas li ntawd, ntxiv nrog Alpha-GPC tuaj yeem pab cov txheej txheem rog rog thiab txhawb cov lipid metabolism. Qhov no yog vim choline lub luag haujlwm ua lipophilic nutrient. Kev noj qab haus huv qib ntawm cov khoom noj no kom ntseeg tau tias cov roj ntsha muaj nyob rau hauv cov cell mitochondria, uas tuaj yeem hloov cov rog no rau hauv ATP lossis lub zog.

Kev cai tshiab

Alpha GPC tau siv rau ntau tshaj 10 xyoo. Tam sim no, Alpha GPC yog cov khoom noj khoom haus tshiab hauv Nyij Pooj thiab feem ntau siv rau hauv kev tsim cov khoom noj khoom haus. Tsis tas li ntawd, Tebchaws Meskas, Canada, Switzerland thiab lwm lub tebchaws tau pom zoo los yog tso cai rau Alpha GPC ntxiv rau cov zaub mov tom qab Nyiv. Hauv Tebchaws Meskas, Alpha GPC tau tswj hwm raws li Cov Khoom Siv Feem Ntau Pom Zoo (GRAS). Hauv Canada, Alpha GPC tau pom zoo ua cov khoom noj qab haus huv.

Kev lag luam kev siv thiab cov khoom lag luam

Raws li cov ntaub ntawv tsis txaus ntawm kev nyab xeeb ntawm Alpha GPC hauv cov menyuam mos, cov poj niam cev xeeb tub, thiab cov poj niam cev xeeb tub, raws li lub hauv paus ntsiab lus ntawm kev tiv thaiv kev pheej hmoo, cov pab pawg saum toj no yuav tsum tsis txhob noj, thiab daim ntawv lo thiab cov lus qhia yuav tsum qhia cov pab pawg tsis haum. Hauv Tebchaws Meskas, Nyiv, Canada thiab lwm lub tebchaws, Alpha GPC tau siv dav hauv zaub mov. Cov khoom lag luam muaj feem cuam tshuam txog kev noj zaub mov, dej haus, gummies thiab lwm yam, thiab txhua yam khoom muaj qhov tseeb thiab pom zoo siv.

Kom muaj nuj nqis thiab pab pawg pom zoo. Piv txwv li, nyob rau hauv lub tebchaws United States, muaj ntau tshaj li 300 cov khoom noj khoom haus rau Alpha GPC ib leeg, nrog rau kev thov cov teebmeem xws li kev txhim kho kev nco thiab kev txawj ntse, kev txhim kho lub cev muaj zog, thiab lwm yam. Cov koob tshuaj txhua hnub yog 300-1200 mg.
Cov xwm txheej tam sim no ntawm kev tsim khoom siv tshuab

Kev tshawb fawb qhia tau hais tias tshuaj synthesis yog ib qho ntawm cov txheej txheem tseem ceeb ntawm Alpha GPC. Siv polyphosphoric acid, choline chloride, R-3-chloro-1,2-propanediol, sodium hydroxide thiab dej ua raw khoom, tom qab condensation thiab esterification cov tshuaj tiv thaiv, nws yog decolorized, impurity tshem tawm, concentrated, refined thiab qhuav. tuaj yeem tau txais los ntawm lwm cov txheej txheem. Txawm li cas los xij, cov tshuaj siv tshuaj ib txwm siv, tshuaj hydrolysis, tshuaj alcoholysis thiab lwm txoj hauv kev tau ntsib teeb meem xws li kev ua qias tuaj ib puag ncig, tus nqi siab, thiab cov txheej txheem npaj nyuaj.

Nyob rau hauv xyoo tas los no, kev npaj ntawm Alpha GPC los ntawm bioenzymatic txoj kev tau txais kev saib xyuas ntau dua. Aqueous-theem enzymatic txoj kev, uas tsis yog-aqueous-theem enzymatic txoj kev, thiab lwm yam tau tshwm sim ib tom qab. Piv nrog rau cov txheej txheem tshuaj, kev npaj ntawm Alpha GPC los ntawm bioenzymatic txoj kev muaj cov tshuaj tiv thaiv me me thiab cov txheej txheem yooj yim. , siab catalytic efficiency thiab haum rau loj-scale lag luam ntau lawm.

Suzhou Myland Pharm & Nutrition Inc. yog ib lub chaw tsim tshuaj paus FDA uas muab cov khoom zoo thiab siab dawb huv Alpha GPC Supplement hmoov.

Ntawm Suzhou Myland Pharm peb tau cog lus los muab cov khoom lag luam zoo tshaj plaws ntawm tus nqi zoo tshaj. Peb Alpha GPC Supplement hmoov yog nruj me ntsis soj ntsuam rau purity thiab potency, kom ntseeg tau tias koj tau txais cov khoom zoo uas koj tuaj yeem ntseeg tau. Txawm hais tias koj xav txhawb nqa kev noj qab haus huv ntawm tes, txhawb koj lub cev tiv thaiv kab mob lossis txhim kho kev noj qab haus huv tag nrho, peb Alpha GPC Supplement hmoov yog qhov kev xaiv zoo tshaj.

Nrog 30 xyoo ntawm kev paub thiab tsav los ntawm cov cuab yeej siv siab thiab cov tswv yim zoo R & D, Suzhou Myland Pharm tau tsim ntau yam khoom sib tw thiab dhau los ua lub neej tshiab kev tshawb fawb ntxiv, kev cai synthesis thiab kev tsim cov tuam txhab.

Tsis tas li ntawd, Suzhou Myland Pharm kuj yog ib lub chaw tsim tshuaj paus FDA. Lub tuam txhab R&D cov peev txheej, cov chaw tsim khoom, thiab cov cuab yeej tshuaj ntsuam xyuas yog niaj hnub thiab muaj ntau yam, thiab tuaj yeem tsim cov tshuaj los ntawm milligrams mus rau tons hauv nplai, thiab ua raws li ISO 9001 cov qauv thiab cov khoom tshwj xeeb GMP.

Alpha GPC paub tias yog hygroscopic, txhais tau tias nws nqus dej noo los ntawm huab cua ib puag ncig. Vim li no, cov tshuaj yuav tsum tau muab cia rau hauv lub thawv airtight thiab yuav tsum tsis txhob raug huab cua rau lub sijhawm ntev.

Kev xav kawg

Alpha GPC yog siv los xa choline mus rau lub hlwb hla cov ntshav-hlwb barrier. Nws yog ib qho precursor rau acetylcholine, ib qho neurotransmitter uas txhawb kev paub txog kev noj qab haus huv. Cov tshuaj Alpha GPC tuaj yeem siv los pab koj txoj kev paub txog kev noj qab haus huv los ntawm kev txhim kho kev nco, kev kawm, thiab kev xav. Kev tshawb fawb tseem qhia tau tias Alpha GPC pab ua kom lub cev muaj zog thiab cov leeg muaj zog.