Choline Alfoscerate,tseem hu ua Alpha-GPC, yog ib yam khoom uas tau rho tawm los ntawm cov nroj tsuag lecithin, tab sis nws tsis yog phospholipid, tab sis yog phospholipid uas tau los ntawm cov tshuaj Lipophilic fatty acid. Alpha-GPC yog ib yam khoom noj muaj ntau yam uas pom muaj nyob rau hauv txhua lub hlwb ntawm cov tsiaj txhu. Vim tias nws yog hydrophilic heev, nws raug nqus sai tom qab noj. GPC yog ib qho ua ntej ntawm acetylcholine (ACh) thiab muaj kev cog lus zoo hauv kev ua haujlwm choline tsis zoo.
GPC yooj yim hla dhau cov ntshav-lub hlwb thaiv thiab muab qhov chaw ntawm choline rau biosynthesis ntawm ACh thiab phosphatidylcholine. Phospholipids thiab acetylcholine, thaum ua tiav ntawm qib zoo tshaj plaws, txhawb kev paub, kev puas siab puas ntsws thiab kev noj qab haus huv ntawm lub hlwb. Tsis tas li ntawd, qhov sib npaug ntawm Alpha-GPC thiab Ach tuaj yeem txhawb cov txheej txheem physiological thiab txhim kho kev ua tau zoo ntawm lub cev. ACh koom nrog hauv cov leeg nqaij thiab yog lub neurotransmitter tseem ceeb uas tswj cov lus teb physiological rau kev tawm dag zog.
Vim tias txhua qhov kev txav ntawm cov leeg nqaij muaj feem cuam tshuam nrog kev cog lus, thiab kev cog lus muaj feem cuam tshuam nrog qhov muaj nyob hauv cellular ACh concentration, kev ua kom ACh siab tshaj plaws ua rau cov leeg nqaij ua tau zoo dua. Piv rau lwm cov choline precursors, Alpha-GPC muaj kev nyab xeeb thiab ua tau zoo nce cov choline hauv cov ntshav thiab lub hlwb. Ntau txoj kev tshawb fawb tau lees paub ntau yam txiaj ntsig ntawm Alpha-GPC thiab qhia tias kev noj tshuaj ntxiv yuav ua lub luag haujlwm tseem ceeb hauv kev txhim kho kev ua haujlwm ntawm lub paj hlwb, kev ua haujlwm ntawm lub cev, thiab kev txhim kho kev nco.
Alpha-GPC ua haujlwm tau zoo
Txhim kho lub zog ntawm lub hlwb
Qhov ntau dua ntawm cov hlwb hlwb hauv lub hlwb, lawv lub zog muaj zog dua, lawv xa cov cim hlwb sai dua, thiab lub hlwb lub zog ua haujlwm muaj zog dua. Alpha-GPC tuaj yeem txhim kho kev ua haujlwm ntawm lub hlwb los ntawm kev txhim kho lub zog ntawm cov hlwb hlwb thiab lub peev xwm xa cov cim hlwb. Hais txog kev txhim kho cholinergic neurotransmission, kev xa cov cim ntawm cov hlwb hlwb vam khom kev xa cov neurotransmitters, thiab acetylcholine yog tus neeg xa xov tseem ceeb thiab neurotransmitter uas ua kom muaj kev xav thiab tswj kev sib koom tes ntawm lub hlwb thiab tag nrho lub cev. Alpha-GPC tuaj yeem raug rhuav tshem mus rau hauv 3-glycerol phosphate thiab choline hauv lub hlwb thiab yog qhov muab acetylcholine zoo tshaj plaws. Nws tuaj yeem txhim kho kev nco thiab txhim kho kev xav los ntawm kev txhawb nqa kev tsim thiab tso tawm ntawm acetylcholine hauv lub hlwb. Hais txog kev txhim kho kev ruaj khov thiab kev ntws ntawm cov hlwb hlwb, Alpha-GPC tuaj yeem txhawb nqa kev tsim cov phosphoinositide, yog li txhim kho kev ruaj khov thiab kev ntws ntawm cov hlwb hlwb hlwb. Neurons nrog cov qauv tiav tuaj yeem xa cov ntaub ntawv zoo dua thiab txhim kho lub cev xav tau. Siv.
Tiv thaiv cov hlab ntsha
Cov yam tseem ceeb ntawm kev loj hlob ntawm cov ntaub so ntswg ntawm lub paj hlwb, uas yog cov yam tseem ceeb ntawm cov hlab ntsha, tuaj yeem tswj kev sib txawv ntawm cov hlwb thiab txhawb kev tsim cov kev sib txuas ntawm cov hlab ntsha tshiab. Alpha-GPC tuaj yeem txhawb kev tso tawm ntawm ntau yam yam tseem ceeb ntawm cov hlab ntsha thiab ua kom cov kab ke ua haujlwm cuam tshuam nrog kev ciaj sia ntawm cov hlwb, yog li ua rau muaj kev cuam tshuam rau cov hlab ntsha. Txhim kho lub cev qib kev paub. Tib lub sijhawm, Alpha-GPC kuj tseem tuaj yeem txhawb kev tso tawm ntawm cov tshuaj hormones loj hlob thiab tswj kev noj qab haus huv ntawm lub cev los ntawm kev nce qib ntawm cov tshuaj hormones loj hlob ntawm lub cev.
Tshuaj tua kab mob
Kev oxidation thiab o yog cov ua rau lub hlwb laus thiab tuag. Alpha-GPC tuaj yeem tshem tawm cov free radicals hauv lub cev, tawm tsam kev ntxhov siab oxidative, thiab tseem tuaj yeem txo qhov o xws li nuclear factor NF-κB, tumor necrosis factor TNF-α, thiab interleukin IL-6. Kev tso tawm ntawm cov yam ntxwv tawm tsam lub hlwb o, yog li ntawd thim rov qab qhov kev poob qis ntawm kev ua haujlwm ntawm lub hlwb thiab tiv thaiv kev tshwm sim thiab kev loj hlob ntawm cov kab mob neurodegenerative. Cov teebmeem cuam tshuam tau txhawb nqa los ntawm cov teebmeem hauv kev kho mob.
Hauv kev tshawb fawb "Qhov Cuam Tshuam ntawm Alpha-GPC rau Kev Tsis Nco Qab Raws Li Lub Hnub Nyoog", 4 tus neeg tau txais placebo, thiab 5 tus neeg ntxiv tau txais Alpha-GPC (1200 mg / hnub), tom qab noj tas li rau 3 lub hlis, 16 lub electrodes tau siv los kaw cov nthwv dej hauv lub hlwb rau 5 feeb thaum cov neeg koom nrog tseem sawv thiab so. Cov txiaj ntsig tau qhia tias piv rau placebo, Alpha-GPC muaj peev xwm ua rau muaj qhov sib piv ntawm cov nthwv dej hauv lub hlwb sai tshaj plaws, thaum muaj qhov feem cuam tshuam txo qis cov zaus qeeb tshaj plaws. Ntawd yog, nws tuaj yeem txhim kho lub hlwb muaj zog ntawm cov neeg hnub nyoog nruab nrab thiab ncua kev laus ntawm lub cev.
Tswj kev xav
Dopamine tuaj yeem ua rau tib neeg zoo siab, thiab serotonin thiab gamma-aminobutyric acid tuaj yeem tswj lub cev lub siab. Alpha-GPC tuaj yeem txhawb kev tso tawm ntawm dopamine, tswj kev qhia tawm ntawm dopamine transporters, txhim kho dopamine neurotransmission hauv lub hlwb, thiab nce qib ntawm serotonin hauv striatum thiab prefrontal cortex; nws kuj tseem tuaj yeem txhawb nqa γ- Kev tso tawm ntawm aminobutyric acid txo qhov insomnia, yog li ua rau nws cov tshuaj tiv thaiv kev nyuaj siab, kev ntxhov siab thiab kev ruaj khov ntawm lub siab.
Ntxiv rau, Alpha-GPC kuj zoo li muaj peev xwm txhim kho kev nqus ntawm cov hlau uas tsis yog heme hauv cov zaub mov, zoo ib yam li cov nyhuv ntawm vitamin C ntawm 2: 1 piv nrog hlau, yog li Alpha-GPC raug suav hais tias yog, lossis tsawg kawg yog pab txhawb rau, kev txhim kho ntawm cov khoom nqaij. Qhov tshwm sim ntawm kev nqus hlau uas tsis yog heme. Ntxiv rau, kev ntxiv nrog Alpha-GPC kuj tseem tuaj yeem pab cov txheej txheem hlawv rog thiab txhawb nqa cov metabolism lipid. Qhov no yog vim choline lub luag haujlwm ua cov khoom noj khoom haus lipophilic. Cov qib noj qab haus huv ntawm cov khoom noj khoom haus no ua kom ntseeg tau tias cov fatty acids muaj rau cov cell mitochondria, uas tuaj yeem hloov cov rog no mus rau hauv ATP lossis lub zog.
Cov kev hloov tshiab ntawm txoj cai lij choj
Alpha GPC tau siv rau ntau tshaj 10 xyoo. Tam sim no, Alpha GPC yog cov khoom siv tshiab hauv Nyiv Pooj thiab feem ntau siv rau hauv kev tsim cov khoom noj khoom haus ua haujlwm. Tsis tas li ntawd, Tebchaws Meskas, Canada, Switzerland thiab lwm lub tebchaws tau pom zoo lossis tso cai rau Alpha GPC ntxiv rau hauv cov khoom noj tom qab Nyiv Pooj. Hauv Tebchaws Meskas, Alpha GPC raug tswj hwm ua Tshuaj Feem Ntau Paub Zoo tias Muaj Kev Nyab Xeeb (GRAS). Hauv Canada, Alpha GPC raug pom zoo ua cov khoom noj khoom haus ntuj.
Cov ntawv thov kev lag luam thiab cov qauv khoom
Vim tias tsis muaj cov ntaub ntawv txaus txog kev nyab xeeb ntawm Alpha GPC rau cov menyuam mos, cov poj niam cev xeeb tub, thiab cov poj niam pub niam mis, raws li lub hauv paus ntsiab lus ntawm kev tiv thaiv kev pheej hmoo, cov pab pawg saum toj no yuav tsum tsis txhob noj nws, thiab daim ntawv lo thiab cov lus qhia yuav tsum qhia txog pab pawg tsis haum. Hauv Tebchaws Meskas, Nyiv Pooj, Canada thiab lwm lub tebchaws, Alpha GPC tau siv dav hauv zaub mov. Cov khoom cuam tshuam suav nrog cov khoom noj khoom haus, dej haus, gummies thiab lwm pawg, thiab txhua yam khoom muaj lub luag haujlwm meej thiab pom zoo kom siv.
Qhov ntau thiab cov pab pawg pom zoo. Piv txwv li, hauv Tebchaws Meskas, muaj ntau dua 300 cov tshuaj noj rau Alpha GPC ib leeg, nrog rau cov txiaj ntsig suav nrog kev txhim kho kev nco thiab kev ua haujlwm ntawm lub hlwb, txhim kho kev ua haujlwm ntawm lub cev, thiab lwm yam. Cov tshuaj noj txhua hnub yog 300-1200 mg.
Cov xwm txheej tam sim no ntawm kev siv tshuab tsim khoom
Kev tshawb fawb qhia tau hais tias kev tsim tshuaj lom neeg yog ib qho ntawm cov txheej txheem tseem ceeb ntawm Alpha GPC. Siv polyphosphoric acid, choline chloride, R-3-chloro-1,2-propanediol, sodium hydroxide thiab dej ua cov khoom siv raw, tom qab condensation thiab esterification reaction, nws yog decolorized, impurity tshem tawm, concentrated, refined thiab qhuav. tuaj yeem tau txais los ntawm lwm cov txheej txheem. Txawm li cas los xij, kev tsim tshuaj lom neeg ib txwm muaj, tshuaj hydrolysis, tshuaj alcohollysis thiab lwm txoj hauv kev txhua tus ntsib teeb meem xws li kev ua qias tuaj ib puag ncig, tus nqi siab, thiab cov txheej txheem npaj nyuaj.
Nyob rau hauv xyoo tas los no, kev npaj Alpha GPC los ntawm cov txheej txheem bioenzymatic tau txais kev saib xyuas ntau dua. Cov txheej txheem enzymatic aqueous-phase, cov txheej txheem enzymatic tsis-aqueous-phase, thiab lwm yam tau tshwm sim ib qho tom qab ib qho. Piv nrog cov txheej txheem tshuaj lom neeg, kev npaj Alpha GPC los ntawm cov txheej txheem bioenzymatic muaj cov xwm txheej tsis tshua muaj zog thiab cov txheej txheem yooj yim. , kev ua haujlwm catalytic siab thiab tsim nyog rau kev tsim khoom lag luam loj.
Suzhou Myland Pharm & Nutrition Inc. yog ib lub chaw tsim khoom uas tau sau npe los ntawm FDA uas muab cov hmoov Alpha GPC Supplement zoo thiab huv si.
Ntawm Suzhou Myland Pharm peb cog lus tias yuav muab cov khoom zoo tshaj plaws rau tus nqi zoo tshaj plaws. Peb cov hmoov Alpha GPC Supplement tau raug kuaj xyuas kom huv si thiab muaj zog, kom ntseeg tau tias koj tau txais cov tshuaj zoo uas koj ntseeg siab tau. Txawm koj xav txhawb kev noj qab haus huv ntawm tes, txhawb koj lub cev tiv thaiv kab mob lossis txhim kho kev noj qab haus huv tag nrho, peb cov hmoov Alpha GPC Supplement yog qhov kev xaiv zoo tshaj plaws.
Nrog 30 xyoo ntawm kev paub dhau los thiab tsav los ntawm cov thev naus laus zis siab thiab cov tswv yim R&D zoo tshaj plaws, Suzhou Myland Pharm tau tsim ntau yam khoom sib tw thiab dhau los ua lub tuam txhab tsim khoom noj khoom haus tshiab, kev tsim khoom tshwj xeeb thiab kev tsim khoom.
Ntxiv rau qhov ntawd, Suzhou Myland Pharm kuj yog ib lub chaw tsim khoom uas tau sau npe los ntawm FDA. Lub tuam txhab cov peev txheej R&D, cov chaw tsim khoom, thiab cov cuab yeej siv tshuaj ntsuam xyuas yog niaj hnub thiab muaj ntau yam, thiab tuaj yeem tsim cov tshuaj los ntawm milligrams mus rau tons hauv qhov ntsuas, thiab ua raws li ISO 9001 cov qauv thiab cov lus qhia tsim khoom GMP.
Alpha GPC paub tias yog hygroscopic, txhais tau tias nws nqus cov dej noo ntawm huab cua ib puag ncig. Vim li no, cov tshuaj ntxiv yuav tsum tau khaws cia rau hauv cov thawv kaw thiab yuav tsum tsis txhob raug cua ntev.
Cov kev xav kawg
Alpha GPC siv los xa choline mus rau lub hlwb hla cov ntshav-lub hlwb thaiv. Nws yog ib qho ua ntej rau acetylcholine, ib qho neurotransmitter uas txhawb kev noj qab haus huv ntawm kev paub. Alpha GPC cov tshuaj ntxiv tuaj yeem siv los pab koj txoj kev noj qab haus huv ntawm kev paub los ntawm kev txhim kho kev nco, kev kawm, thiab kev tsom mus rau. Kev tshawb fawb kuj qhia tau tias Alpha GPC pab ua kom lub cev muaj zog thiab cov leeg muaj zog.
Lus Ceeb Toom: Tsab xov xwm no tsuas yog rau cov ntaub ntawv dav dav xwb thiab yuav tsum tsis txhob txhais hais tias yog cov lus qhia kho mob. Qee cov ntaub ntawv hauv blog los ntawm Is Taws Nem thiab tsis yog kev tshaj lij. Lub vev xaib no tsuas yog lub luag haujlwm rau kev txheeb xyuas, tsim hom ntawv thiab kho cov ntawv xwb. Lub hom phiaj ntawm kev xa cov ntaub ntawv ntxiv tsis tau txhais hais tias koj pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Ib txwm sab laj nrog tus kws kho mob ua ntej siv cov tshuaj ntxiv lossis hloov pauv koj txoj kev kho mob.
Lub sijhawm tshaj tawm: Lub Kaum Hli-06-2024
