Choline Alfoscerate yog dab tsi thiab yuav pab tau koj lub hlwb li cas?

Raws li ib tug endogenous tshuaj nyob rau hauv tib neeg lub cev, L-α-glycerophosphocholine tuaj yeem nkag mus rau cov ntshav-hlwb barrier thiab muaj bioavailability siab heev. Nws yog cov khoom noj muaj txiaj ntsig zoo uas tseem ceeb rau tib neeg lub cev. "Cov ntshav-hlwb barrier yog ib tug ntom, 'phab ntsa'-zoo li cov qauv ntawm lub capillary plexuses ntawm lub paj hlwb. L-α-glycerophosphocholine tau yooj yim nkag mus rau hauv cov ntshav-hlwb barrier thiab ua lub luag hauj lwm nyob rau hauv kev txhim kho kev nco, txhim kho kev xav, thiab nws. muaj cov txiaj ntsig zoo hauv kev txo cov kev ntxhov siab, ua kom lub siab nyob ruaj khov, thiab ua kom cov leeg muaj zog thiab kev ua siab ntev "Cov khoom noj muaj txiaj ntsig ntawm L-α-glycerophosphocholine feem ntau tshwm sim hauv 5 yam.

Ib qho yog los txhim kho lub hlwb ua haujlwm. Cov paj hlwb ntau dua nyob rau hauv lub hlwb, lawv lub zog loj dua, lawv kis tau cov paj hlwb sai dua, thiab lub hlwb muaj zog ua haujlwm ntau dua. L-α-glycerophosphocholine tuaj yeem txhim kho lub hlwb ua haujlwm los ntawm kev txhim kho qhov tseem ceeb ntawm cov paj hlwb thiab kev muaj peev xwm kis tau ntawm cov paj hlwb. Nyob rau hauv cov nqe lus ntawm kev txhim kho cholinergic neurotransmission, teeb liab kis tau tus mob ntawm paj hlwb cia siab rau kev sib kis ntawm neurotransmitters, thiab acetylcholine yog ib tug tseem ceeb tshuaj xa xov thiab neurotransmitter uas ua kom muaj kev xav thiab tswj kev sib koom tes ntawm lub hlwb thiab tag nrho lub cev.

L-α-glycerophosphocholine tuaj yeem decomposed rau hauv 3-glycerol phosphate thiab choline hauv lub hlwb thiab yog cov khoom siv tau zoo tshaj plaws ntawm acetylcholine. Nws tuaj yeem txhim kho kev nco thiab txhim kho kev xav los ntawm kev txhawb nqa cov synthesis thiab tso tawm ntawm acetylcholine hauv lub hlwb. Nyob rau hauv cov nqe lus ntawm kev txhim kho cov stability thiab fluidity ntawm cell membranes, L-α-glycerophosphocholine yuav txhawb lub synthesis ntawm phosphoinositide, yog li txhim kho cov stability thiab fluidity ntawm cell membranes. Neurons nrog cov qauv tsis zoo tuaj yeem xa cov ntaub ntawv zoo dua. Txhim kho lub cev kev xav agility.

Qhov thib ob yog kev noj haus thiab kev tiv thaiv paj hlwb. Neurotrophic yam, kev loj hlob ntawm cov paj hlwb, tuaj yeem tswj cov qia cell sib txawv thiab txhawb kev tsim cov kev sib txuas tshiab ntawm neural. L-α-glycerophosphocholine tuaj yeem txhawb nqa kev tso tawm ntawm ntau yam neurotrophic yam thiab ua kom muaj kev cuam tshuam txog kev muaj sia nyob ntawm tes, yog li nws ua rau muaj kev tiv thaiv neuroprotective thiab txhim kho lub cev kev txawj ntse. Nyob rau tib lub sijhawm, L-α-glycerophosphocholine tuaj yeem txhawb kev tso tawm ntawm cov tshuaj hormones loj hlob thiab tswj lub cev kev noj qab haus huv los ntawm kev ua kom lub cev loj hlob cov tshuaj hormones.

Qhov thib peb yog antioxidant. Oxidation thiab o yog lub ntsiab ua rau kev laus thiab kev tuag ntawm hlwb hlwb. L-α-glycerophosphocholine tuaj yeem tshem tawm cov dawb radicals hauv lub cev, tawm tsam oxidative kev nyuaj siab, thiab tseem tuaj yeem txo cov teeb meem nuclear NF-κB, qog necrosis factor TNF-α, thiab interleukins. Kev tso tawm ntawm cov teeb meem inflammatory xws li IL-6 tiv thaiv lub hlwb mob, yog li cuam tshuam qhov poob ntawm kev txawj ntse thiab tiv thaiv qhov tshwm sim thiab kev loj hlob ntawm cov kab mob neurodegenerative.

Cov teebmeem cuam tshuam tau raug txhawb los ntawm kev kho mob. Hauv txoj kev tshawb no "Cov nyhuv ntawm L-α-glycerophosphocholine ntawm lub hnub nyoog ntsig txog kev nco tsis zoo", 4 cov ntsiab lus tau muab cov placebo, thiab lwm yam 5 yam tau muab tom qab noj L-α-glycerophosphocholine (1200 mg / hnub) ntawm qhov ncauj rau 3 lub hlis. , 16 electrodes tau siv los sau cov suab paj nruag rau 5 feeb thaum cov ntsiab lus tsaug zog thiab so. Cov txiaj ntsig tau pom tias piv rau cov placebo, L-alpha-glycerophosphocholine tau nce qhov feem pua ​​​​ntawm cov hlwb nrawm tshaj plaws thaum muaj kev xav txo qis qis tshaj plaws. Ntawd yog, nws tuaj yeem txhim kho lub hlwb tseem ceeb ntawm cov neeg laus nruab nrab thiab ncua kev laus ntawm lub cev.

Qhov thib plaub yog tswj kev xav. Dopamine tuaj yeem ua rau tib neeg zoo siab, thiab serotonin thiab gamma-aminobutyric acid tuaj yeem tswj lub cev lub siab. L-α-glycerophosphocholine tuaj yeem txhawb kev tso tawm ntawm dopamine, nce-tswj cov kev qhia ntawm dopamine transporters, txhim kho dopamine neurotransmission hauv lub hlwb, thiab nce qib ntawm serotonin hauv striatum thiab prefrontal cortex; Nws kuj tseem tuaj yeem txhawb nqa endogenous Qhov tso tawm ntawm γ-aminobutyric acid hauv kev sib deev cortical cov ntaub so ntswg relieves insomnia, yog li exerting nws anti-depressant, ntxhov siab vim-relieving thiab mus ob peb vas-stabilizing teebmeem.

Qhov thib tsib yog txhawm rau txhim kho kev ua kis las. Thaum lub sij hawm qoj ib ce, L-alpha-glycerophosphocholine kuj txhim kho lub cev muaj pes tsawg leeg los ntawm kev ua kom cov leeg nqaij thiab txhim kho tag nrho cov kev ua haujlwm metabolic los ntawm kev ua kom loj hlob hormone ntau lawm thiab lub zog tso zis. Tsis tas li ntawd, L-α-glycerophosphocholine kuj tseem tuaj yeem ua kom cov kab mob sib kis tau zoo, txhim kho kev ua haujlwm ntawm kev sib txuas neuromuscular, ua rau kom muaj kev cog lus thiab kev ua siab ntev ntawm cov leeg pob txha, yog li ua kom lub cev qoj ib ce, tiv thaiv qaug zog, thiab ua kom muaj txiaj ntsig zoo ntawm cov leeg nqaij. . cawv.

Yog li qhov twg tib neeg tuaj yeem tau txais cov khoom noj no nrog ntau qhov txiaj ntsig zoo? Qhov tseeb, L-α-glycerophosphocholine muaj nyob rau hauv ntau yam khoom noj xws li qe, nqaij qaib, thiab zaj sawv trout, tab sis cov ntsiab lus feem ntau me me. Raws li "Second Edition of the US General Food Choline Content Database" luam tawm los ntawm Tebchaws Meskas Lub Tsev Haujlwm Saib Xyuas Kev Ua Liaj Ua Teb, cov ntsiab lus ntawm L-α-glycerophosphocholine hauv tag nrho 630 zaub mov hauv 22 pawg tau pom tias L-α-glycerophosphocholine ib 100 grams ntawm cov khoom noj Cov ntsiab lus ntawm glycerophosphocholine nyob ntawm 0 txog 190 mg. Yog li ntawd, txhawm rau ua kom tau raws li qhov xav tau ntawm tib neeg lub cev kev loj hlob, kev loj hlob thiab cov metabolism, cov tshuaj ntxiv tuaj yeem ua kom tsim nyog.

Cov tshuaj synthesis yog ib qho ntawm cov txheej txheem tseem ceeb ntawm L-α-glycerophosphocholine. Siv polyphosphoric acid, choline chloride, R-3-chloro-1,2-propanediol, sodium hydroxide thiab dej ua raw khoom, tom qab condensation thiab esterification cov tshuaj tiv thaiv, nws yog decolorized, impurity tshem tawm, concentrated, refined thiab qhuav. L-α-glycerophosphocholine ua los ntawm lwm cov txheej txheem tuaj yeem muab ntxiv rau cov dej qab zib, dej qab zib kis las, kas fes, gummies, oatmeal zog tuav, thiab lwm yam, thiab tuaj yeem ua rau nws cov khoom noj muaj txiaj ntsig zoo raws li lub hom phiaj kom tau raws li kev noj qab haus huv ntau yam ntawm cov neeg siv khoom. xav tau.

Hauv Tebchaws Meskas, Nyiv, Canada thiab lwm lub tebchaws, L-α-glycerophosphocholine tau siv dav hauv cov khoom noj. Cov khoom lag luam muaj feem cuam tshuam txog kev noj zaub mov, dej haus, gummies thiab lwm pawg, thiab txhua yam khoom muaj cov haujlwm meej meej, pom zoo noj ntau npaum li cas thiab cov pab pawg pom zoo.

Suzhou Myland Pharm & Nutrition Inc.is yog lub chaw tsim khoom lag luam FDA tso npe uas muab cov khoom zoo thiab siab dawb huv Alpha GPC hmoov.

Ntawm Suzhou Myland Pharm peb tau cog lus los muab cov khoom lag luam zoo tshaj plaws ntawm tus nqi zoo tshaj. Peb Alpha GPC hmoov yog nruj me ntsis soj ntsuam rau purity thiab potency, kom ntseeg tau tias koj tau txais cov khoom zoo uas koj tuaj yeem ntseeg tau. Txawm hais tias koj xav txhawb nqa kev noj qab haus huv ntawm tes, txhawb koj lub cev tiv thaiv kab mob lossis txhim kho kev noj qab haus huv tag nrho, peb Alpha GPC hmoov yog qhov kev xaiv zoo tshaj.

Nrog 30 xyoo ntawm kev paub thiab tsav los ntawm cov cuab yeej siv siab thiab cov tswv yim zoo R & D, Suzhou Myland Pharm tau tsim ntau yam khoom sib tw thiab dhau los ua lub neej tshiab kev tshawb fawb ntxiv, kev cai synthesis thiab kev tsim cov tuam txhab.

Tsis tas li ntawd, Suzhou Myland Pharm tseem yog FDA-sau npe chaw tsim khoom. Lub tuam txhab R&D cov peev txheej, cov chaw tsim khoom, thiab cov cuab yeej tshuaj ntsuam xyuas yog niaj hnub thiab muaj ntau yam, thiab tuaj yeem tsim cov tshuaj los ntawm milligrams mus rau tons hauv nplai, thiab ua raws li ISO 9001 cov qauv thiab cov khoom tshwj xeeb GMP.