Choline Alfoscerate yog dab tsi thiab nws pab tau koj lub hlwb li cas?

Ua ib yam khoom endogenous hauv tib neeg lub cev, L-α-glycerophosphocholine tuaj yeem nkag mus rau hauv cov ntshav-lub hlwb thaiv thiab muaj bioavailability siab heev. Nws yog ib qho khoom noj khoom haus zoo uas tseem ceeb rau tib neeg lub cev. "Lub ntshav-lub hlwb thaiv yog ib qho ntom ntom, 'phab ntsa'-zoo li cov qauv ntawm cov capillary plexuses ntawm lub hlwb. L-α-glycerophosphocholine tuaj yeem nkag mus rau hauv cov ntshav-lub hlwb thaiv thiab ua lub luag haujlwm hauv kev txhim kho kev nco, txhim kho kev xav, thiab Nws muaj peev xwm pab tau hauv kev txo kev ntxhov siab, tswj kev xav, thiab ua kom cov leeg muaj zog thiab ua siab ntev. "Cov txiaj ntsig ntawm kev noj haus ntawm L-α-glycerophosphocholine feem ntau pom hauv 5 yam.

Ib qho yog los txhim kho kev ua haujlwm ntawm lub hlwb. Yog tias muaj ntau cov hlwb ntawm lub hlwb, lawv lub zog yuav muaj zog dua, lawv xa cov cim ntawm lub hlwb sai dua, thiab lub hlwb lub zog ua haujlwm yuav muaj zog dua. L-α-glycerophosphocholine tuaj yeem txhim kho kev ua haujlwm ntawm lub hlwb los ntawm kev txhim kho lub zog ntawm cov hlwb ntawm lub hlwb thiab kev xa cov cim ntawm lub hlwb. Hais txog kev txhim kho cholinergic neurotransmission, kev xa cov cim ntawm cov hlwb ntawm lub hlwb vam khom kev xa cov neurotransmitters, thiab acetylcholine yog tus neeg xa xov tseem ceeb thiab neurotransmitter uas ua kom muaj kev xav thiab tswj kev sib koom tes ntawm lub hlwb thiab tag nrho lub cev.

L-α-glycerophosphocholine tuaj yeem raug rhuav tshem mus rau hauv 3-glycerol phosphate thiab choline hauv lub hlwb thiab yog qhov muab acetylcholine zoo tshaj plaws. Nws tuaj yeem txhim kho kev nco thiab txhim kho kev xav los ntawm kev txhawb nqa kev tsim thiab tso tawm ntawm acetylcholine hauv lub hlwb. Hais txog kev txhim kho kev ruaj khov thiab kev ntws ntawm cov cell membranes, L-α-glycerophosphocholine tuaj yeem txhawb nqa kev tsim cov phosphoinositide, yog li txhim kho kev ruaj khov thiab kev ntws ntawm cov cell membranes. Cov neurons nrog cov qauv zoo tuaj yeem xa cov ntaub ntawv zoo dua. Txhim kho lub cev txoj kev xav.

Qhov thib ob yog kev noj haus thiab kev tiv thaiv cov hlab ntsha. Cov yam ntxwv neurotrophic, cov yam ntxwv kev loj hlob ntawm cov ntaub so ntswg paj hlwb, tuaj yeem tswj hwm kev sib txawv ntawm cov hlwb thiab txhawb kev tsim cov kev sib txuas tshiab ntawm cov hlab ntsha. L-α-glycerophosphocholine tuaj yeem txhawb kev tso tawm ntawm ntau yam neurotrophic yam ntxwv thiab ua kom cov kab ke signaling cuam tshuam nrog kev ciaj sia ntawm cov hlwb, yog li nws ua rau muaj kev cuam tshuam neuroprotective thiab txhim kho lub cev lub peev xwm paub. Tib lub sijhawm, L-α-glycerophosphocholine kuj tseem tuaj yeem txhawb kev tso tawm ntawm cov tshuaj hormones loj hlob thiab tswj kev noj qab haus huv ntawm lub cev los ntawm kev nce qib ntawm cov tshuaj hormones loj hlob ntawm lub cev.

Qhov thib peb yog antioxidant. Kev oxidation thiab o yog cov ua rau lub hlwb laus thiab tuag. L-α-glycerophosphocholine tuaj yeem tshem tawm cov free radicals hauv lub cev, tawm tsam kev ntxhov siab oxidative, thiab tseem tuaj yeem txo cov nuclear factor NF-κB, tumor necrosis factor TNF-α, thiab interleukins. Kev tso tawm ntawm cov yam ntxwv inflammatory xws li IL-6 tiv thaiv kev o ntawm lub hlwb, yog li ntawd thim rov qab qhov kev poob qis ntawm kev ua haujlwm ntawm lub hlwb thiab tiv thaiv kev tshwm sim thiab kev loj hlob ntawm cov kab mob neurodegenerative.

Cov teebmeem tseem ceeb tau txais kev txhawb nqa los ntawm cov teebmeem hauv kev kho mob. Hauv kev tshawb fawb "Cov teebmeem ntawm L-α-glycerophosphocholine rau kev puas tsuaj ntawm lub cim xeeb uas cuam tshuam nrog lub hnub nyoog", 4 tus neeg tau txais placebo, thiab lwm 5 tus neeg tau txais Tom qab noj L-α-glycerophosphocholine (1200 mg / hnub) hauv qhov ncauj rau 3 lub hlis, 16 lub electrodes tau siv los kaw cov nthwv dej hauv lub hlwb rau 5 feeb thaum cov neeg koom nrog sawv thiab so. Cov txiaj ntsig tau qhia tias piv rau placebo, L-alpha-glycerophosphocholine tau nce qhov feem pua ​​​​​​ntawm cov nthwv dej hauv lub hlwb sai tshaj plaws thaum muaj kev nyiam txo qis cov zaus qeeb tshaj plaws. Ntawd yog, nws tuaj yeem txhim kho lub hlwb lub zog ntawm cov neeg hnub nyoog nruab nrab thiab ncua kev laus ntawm lub cev.

Qhov thib plaub yog tswj kev xav. Dopamine tuaj yeem ua rau tib neeg zoo siab, thiab serotonin thiab gamma-aminobutyric acid tuaj yeem tswj lub cev lub siab. L-α-glycerophosphocholine tuaj yeem txhawb kev tso tawm ntawm dopamine, tswj kev qhia tawm ntawm dopamine transporters, txhim kho dopamine neurotransmission hauv lub hlwb, thiab nce qib ntawm serotonin hauv striatum thiab prefrontal cortex; nws kuj tseem tuaj yeem txhawb nqa endogenous Kev tso tawm ntawm γ-aminobutyric acid hauv cov ntaub so ntswg cortical kev sib deev txo qhov insomnia, yog li ua rau nws cov tshuaj tiv thaiv kev nyuaj siab, kev ntxhov siab-tso thiab kev ruaj khov ntawm lub siab.

Qhov thib tsib yog los txhim kho kev ua kis las. Thaum lub sijhawm ua si, L-alpha-glycerophosphocholine kuj txhim kho lub cev muaj pes tsawg leeg los ntawm kev ua kom cov leeg nqaij loj hlob thiab txhim kho kev ua haujlwm ntawm tag nrho cov metabolism los ntawm kev ua kom cov tshuaj hormones loj hlob sai thiab lub zog tso zis. Tsis tas li ntawd, L-α-glycerophosphocholine kuj tseem tuaj yeem ua kom cov neurotransmitter kis tau sai dua, txhim kho kev ua haujlwm ntawm cov kev sib txuas ntawm cov leeg nqaij, ua rau cov leeg nqaij thiab lub zog ntawm cov leeg pob txha ua haujlwm, yog li ua rau lub cev muaj zog, tiv thaiv kev qaug zog, thiab muaj txiaj ntsig zoo rau kev loj hlob ntawm cov leeg.

Yog li ntawd, tib neeg yuav tau txais cov khoom noj khoom haus no qhov twg nrog ntau yam txiaj ntsig zoo li no? Qhov tseeb, L-α-glycerophosphocholine muaj nyob rau hauv ntau yam khoom noj xws li qe, nqaij qaib, thiab ntses ntses zaj sawv, tab sis cov ntsiab lus feem ntau me me. Raws li "Tsab Thib Ob ntawm US General Food Choline Content Database" luam tawm los ntawm United States Department of Agriculture, cov ntsiab lus ntawm L-α-glycerophosphocholine hauv tag nrho 630 cov khoom noj hauv 22 pawg qhia tau tias L-α-glycerophosphocholine ib 100 grams ntawm cov khoom noj Cov ntsiab lus ntawm glycerophosphocholine ntau ntawm 0 txog 190 mg. Yog li ntawd, txhawm rau kom tau raws li qhov xav tau ntawm tib neeg lub cev loj hlob, kev txhim kho thiab kev ua haujlwm ntawm lub cev, cov tshuaj ntxiv tuaj yeem ua kom haum.

Kev tsim tshuaj lom neeg yog ib qho ntawm cov txheej txheem tseem ceeb ntawm L-α-glycerophosphocholine. Siv polyphosphoric acid, choline chloride, R-3-chloro-1,2-propanediol, sodium hydroxide thiab dej ua cov khoom siv raw, tom qab condensation thiab esterification reaction, nws yog decolorized, impurity tshem tawm, concentrated, refined thiab qhuav. L-α-glycerophosphocholine ua los ntawm lwm cov txheej txheem tuaj yeem ntxiv rau cov dej qab zib, dej haus kis las, kas fes, gummies, oatmeal energy bars, thiab lwm yam, thiab tuaj yeem ua rau nws cov txiaj ntsig zoo rau kev noj qab haus huv kom tau raws li kev noj qab haus huv ntawm cov neeg siv khoom.

Hauv Tebchaws Meskas, Nyiv Pooj, Canada thiab lwm lub tebchaws, L-α-glycerophosphocholine tau siv dav hauv cov khoom noj. Cov khoom lag luam cuam tshuam suav nrog cov khoom noj khoom haus, dej haus, gummies thiab lwm pawg, thiab txhua yam khoom muaj cov haujlwm meej, cov tshuaj pom zoo thiab cov pab pawg pom zoo.

Suzhou Myland Pharm & Nutrition Inc. yog ib lub chaw tsim khoom uas tau sau npe los ntawm FDA uas muab cov hmoov Alpha GPC zoo thiab huv si.

Ntawm Suzhou Myland Pharm peb cog lus tias yuav muab cov khoom zoo tshaj plaws rau tus nqi zoo tshaj plaws. Peb cov hmoov Alpha GPC raug kuaj xyuas kom huv si thiab muaj zog, kom ntseeg tau tias koj tau txais cov tshuaj zoo uas koj ntseeg siab tau. Txawm koj xav txhawb kev noj qab haus huv ntawm tes, txhawb koj lub cev tiv thaiv kab mob lossis txhim kho kev noj qab haus huv tag nrho, peb cov hmoov Alpha GPC yog qhov kev xaiv zoo tshaj plaws.

Nrog 30 xyoo ntawm kev paub dhau los thiab tsav los ntawm cov thev naus laus zis siab thiab cov tswv yim R&D zoo tshaj plaws, Suzhou Myland Pharm tau tsim ntau yam khoom sib tw thiab dhau los ua lub tuam txhab tsim khoom noj khoom haus tshiab, kev tsim khoom tshwj xeeb thiab kev tsim khoom.

Ntxiv rau, Suzhou Myland Pharm kuj yog lub chaw tsim khoom uas tau sau npe los ntawm FDA. Lub tuam txhab cov peev txheej R&D, cov chaw tsim khoom, thiab cov cuab yeej siv tshuaj ntsuam xyuas yog niaj hnub thiab muaj ntau yam, thiab tuaj yeem tsim cov tshuaj los ntawm milligrams mus rau tons hauv qhov ntsuas, thiab ua raws li ISO 9001 cov qauv thiab cov lus qhia tsim khoom GMP.