Dab tsi yog NAD + thiab Vim Li Cas Koj Xav Tau Nws rau Koj Kev Noj Qab Haus Huv?

Nyob rau hauv lub ntiaj teb loj hlob ntawm kev noj qab haus huv thiab kev noj qab haus huv, NAD + tau dhau los ua lus nrov, nyiam cov neeg tshawb fawb thiab cov neeg nyiam noj qab haus huv ib yam nkaus. Tab sis dab tsi yog NAD +? Vim li cas nws thiaj tseem ceeb rau koj txoj kev noj qab haus huv? Cia peb kawm ntxiv txog cov ntaub ntawv tseem ceeb hauv qab no!

NAD + yog dab tsi?

NAD lub npe scientific yog nicotinamide adenine dinucleotide. NAD + muaj nyob rau hauv txhua lub cell ntawm peb lub cev. Nws yog ib qho tseem ceeb metabolite thiab coenzyme nyob rau hauv ntau txoj kev metabolic. Nws kho thiab koom nrog ntau yam txheej txheem lom neeg. Ntau tshaj 300 enzymes nyob ntawm NAD + Ua haujlwm.

NAD+yog lus Askiv abbreviation ntawm Nicotinamide adenine dinucleotide. Nws lub npe tag nrho hauv Suav yog nicotinamide adenine dinucleotide, lossis Coenzyme I luv luv. Raws li ib tug coenzyme uas kis hydrogen ions, NAD + plays lub luag hauj lwm nyob rau hauv ntau yam ntawm tib neeg metabolism, nrog rau glycolysis, Gluconeogenesis, tricarboxylic acid voj voog, thiab lwm yam. Qee cov kev tshawb fawb tau taw qhia tias depletion ntawm NAD + muaj feem xyuam rau lub hnub nyoog, thiab lub physiological mechanisms kho. los ntawm NAD + muaj feem xyuam rau kev laus, cov kab mob metabolic, neuropathy thiab mob qog noj ntshav, suav nrog kev tswj hwm cell homeostasis, sirtuins hu ua "cov noob neej ntev", kho DNA, PARPs tsev neeg cov proteins uas cuam tshuam nrog necroptosis thiab CD38 uas pab hauv calcium signaling.

NAD + ua raws li lub tsheb thauj mus los, nqa cov khoom siv hluav taws xob los ntawm ib lub xov tooj ntawm tes mus rau lwm qhov. Ua ke nrog nws cov molecular counterpart NADH, nws koom nrog ntau yam kev cuam tshuam metabolic los ntawm kev sib pauv hluav taws xob uas tsim cov adenosine triphosphate (ATP), lub cev "zog" molecule.

Yooj yim muab, NAD + yog qhov tseem ceeb rau kev tswj lub cev kev noj qab haus huv thiab sib npaug. Metabolism, redox, DNA tu thiab kho, gene stability, epigenetic regulation, thiab lwm yam. txhua yam xav tau kev koom tes ntawm NAD +.

Yog li ntawd, peb lub cev muaj kev thov siab rau NAD +. NAD + txuas ntxiv ua ke, tawg thiab rov ua dua tshiab hauv cov hlwb kom tswj tau cov qib cellular NAD + ruaj khov.

NAD + yog ib qho tseem ceeb ntawm kev ua haujlwm ntawm tes thiab koom nrog hauv kev muab hluav taws xob thiab kho DNA, ob qho tib si cuam tshuam nrog kev noj qab haus huv.

1) Nws yog dav faib nyob rau hauv tag nrho cov hlwb ntawm tib neeg lub cev thiab koom nyob rau hauv ntau txhiab tus biocatalytic tshua. Nws tuaj yeem txhawb cov metabolism hauv qab zib, rog thiab amino acids, thiab koom nrog hauv kev sib txuas ntawm lub zog. Nws yog ib qho tseem ceeb coenzyme tsim nyog rau tib neeg lub cev.

2) NAD + yog tib lub substrate rau coI-siv enzymes (tsuas yog substrate rau DNA kho enzyme PARP, tsuas yog substrate rau lub neej ntev protein Sirtuins, thiab tib lub substrate rau cyclic ADP ribose synthase CD38/157).

Txawm li cas los xij, thaum muaj hnub nyoog nce, qib ntawm NAD + hauv lub cev txo qis sai. Nws yuav txo qis 50% txhua 20 xyoo. Thaum yuav luag 40 xyoo, NAD + cov ntsiab lus hauv tib neeg lub cev tsuas yog 25% ntawm qhov nws nyob hauv cov menyuam yaus.

Yog tias tib neeg lub hlwb tsis muaj NAD +, mitochondrial dysfunction raug txo qis, DNA kev puas tsuaj kho muaj peev xwm raug txo, thiab lub neej ntev gene protein tsev neeg Sirtuin kuj tsis ua haujlwm, thiab lwm yam. Cov yam tsis zoo no tuaj yeem ua rau apoptosis, tib neeg kab mob, kev laus thiab kev tuag.

Lub luag haujlwm ntawm NAD + hauv Koj Kev Noj Qab Haus Huv Tag Nrho

Anti-aging

NAD + tswj kev sib txuas lus tshuaj ntawm cov nucleus thiab mitochondria, thiab kev sib txuas lus tsis muaj zog yog qhov tseem ceeb ntawm kev laus ntawm tes.

NAD + tuaj yeem tshem tawm cov lej DNA yuam kev thaum lub sijhawm cell metabolism, tswj cov kev qhia ntawm cov noob, tswj cov kev ua haujlwm ntawm cov hlwb, thiab ua rau cov laus ntawm tib neeg lub hlwb.

Kho DNA puas

NAD + yog ib qho tseem ceeb substrate rau DNA kho enzyme PARP, uas muaj feem cuam tshuam rau DNA kho, noob qhia, kev loj hlob ntawm tes, cell ciaj sia taus, chromosome reconstruction, thiab noob stability.

Ua kom lub neej ntev protein

Sirtuins feem ntau hu ua tsev neeg lub neej ntev protein thiab ua lub luag haujlwm tseem ceeb hauv kev ua haujlwm ntawm tes, xws li o, cell loj hlob, circadian atherosclerosis, lub zog metabolism, neuronal muaj nuj nqi, thiab kev nyuaj siab, thiab NAD + yog ib qho tseem ceeb enzyme rau synthesis ntawm cov proteins uas muaj hnub nyoog. .

Activates tag nrho 7 lub neej ntev proteins hauv tib neeg lub cev, ua lub luag haujlwm tseem ceeb hauv cellular stress resistance, zog metabolism, tiv thaiv cell mutation, apoptosis thiab laus.

Muab lub zog

Nws catalyzes ntau lawm ntau tshaj 95% ntawm lub zog xav tau rau lub neej ua ub no. Mitochondria nyob rau hauv tib neeg lub hlwb yog lub zog nroj tsuag ntawm cov hlwb. NAD + yog ib qho tseem ceeb coenzyme hauv mitochondria los tsim lub zog molecule ATP, hloov cov as-ham rau hauv lub zog xav tau los ntawm tib neeg lub cev.

Txhawb cov hlab ntsha regeneration thiab tswj cov hlab ntsha elasticity

Cov hlab ntsha yog cov ntaub so ntswg uas tsis tseem ceeb rau kev ua neej nyob. Thaum peb muaj hnub nyoog, cov hlab ntsha maj mam poob lawv qhov yooj yim thiab ua kom tawv, tuab, thiab nqaim, ua rau "arteriosclerosis."

NAD + tuaj yeem ua kom cov haujlwm ntawm elastin hauv cov hlab ntsha, yog li tswj cov hlab ntsha elasticity thiab tswj cov hlab ntsha.

Txhawb cov metabolism

Metabolism yog suav nrog ntau yam tshuaj lom neeg hauv lub cev. Lub cev yuav txuas ntxiv pauv cov teeb meem thiab lub zog. Thaum qhov kev pauv no nres, lub neej ntawm lub cev kuj yuav xaus.

Xib fwb Anthony thiab nws pab neeg tshawb fawb ntawm University of California, Tebchaws USA, pom tias NAD + tuaj yeem txhim kho kev ua haujlwm qeeb ntawm cov cell metabolism cuam tshuam nrog kev laus, yog li txhim kho tib neeg txoj kev noj qab haus huv thiab kev ua neej ntev.

Tiv thaiv lub plawv mob

Lub plawv yog lub cev tseem ceeb tshaj plaws ntawm tib neeg, thiab qib NAD + hauv lub cev ua lub luag haujlwm tseem ceeb hauv kev tswj hwm lub siab ua haujlwm.

Kev txo qis ntawm NAD + tuaj yeem cuam tshuam nrog kev ua haujlwm ntawm ntau cov kab mob plawv, thiab ntau cov kev tshawb fawb hauv paus kuj tau lees paub qhov cuam tshuam ntawm kev ntxiv NAD + ntawm cov kab mob plawv.

Tiv thaiv kab mob plawv thiab cerebrovascular

Cov kev tshawb fawb tau pom tias yuav luag tag nrho xya subtypes ntawm sirtuins (SIRT1-SIRT7) muaj feem xyuam rau qhov tshwm sim ntawm cov kab mob plawv. Sirtuins raug suav hais tias yog lub hom phiaj agonistic rau kev kho mob plawv, tshwj xeeb tshaj yog SIRT1.

NAD + yog tib lub substrate rau Sirtuins. Kev noj zaub mov kom raws sijhawm ntawm NAD + rau tib neeg lub cev tuaj yeem ua kom tag nrho cov haujlwm ntawm txhua yam ntawm Sirtuins, yog li tiv thaiv kab mob plawv thiab tiv thaiv kab mob plawv.

Txhawb cov plaub hau kev loj hlob

Qhov laj thawj tseem ceeb ntawm cov plaub hau poob yog qhov poob ntawm cov plaub hau niam cell vitality, thiab poob ntawm cov plaub hau niam cell vitality yog vim NAD + qib hauv tib neeg lub cev txo. Cov plaub hau niam hlwb tsis muaj ATP txaus los ua cov plaub hau protein synthesis, yog li poob lawv qhov tseem ceeb thiab ua rau cov plaub hau poob.

Yog li ntawd, ntxiv NAD + tuaj yeem ntxiv dag zog rau lub voj voog acid thiab tsim ATP, kom cov plaub hau niam hlwb muaj peev xwm tsim cov plaub hau protein, yog li txhim kho plaub hau poob.

Qhov twg Yuav Yuav Beta-NAD + Ntxiv Kev Nyab Xeeb Hauv Online

Suzhou Myland Pharm & Nutrition Inc. yog lub chaw tsim khoom lag luam FDA tso npe uas muab cov khoom zoo thiab siab dawb huv NAD + Ntxiv hmoov.

Ntawm Suzhou Myland Pharm peb tau cog lus los muab cov khoom lag luam zoo tshaj plaws ntawm tus nqi zoo tshaj. Peb cov NAD + Ntxiv hmoov yog nruj me ntsis kuaj rau purity thiab potency, xyuas kom koj tau txais cov khoom zoo uas koj tuaj yeem ntseeg tau. Txawm hais tias koj xav txhawb nqa kev noj qab haus huv ntawm tes, txhawb koj lub cev tiv thaiv kab mob lossis txhim kho kev noj qab haus huv tag nrho, peb cov NAD + Ntxiv hmoov yog qhov kev xaiv zoo tshaj.

Nrog 30 xyoo ntawm kev paub thiab tsav los ntawm cov cuab yeej siv siab thiab cov tswv yim zoo R & D, Suzhou Myland Pharm tau tsim ntau yam khoom sib tw thiab dhau los ua lub neej tshiab kev tshawb fawb ntxiv, kev cai synthesis thiab kev tsim cov tuam txhab.

Tsis tas li ntawd, Suzhou Myland Pharm kuj yog ib lub chaw tsim tshuaj paus FDA. Lub tuam txhab R&D cov peev txheej, cov chaw tsim khoom, thiab cov cuab yeej tshuaj ntsuam xyuas yog niaj hnub thiab muaj ntau yam, thiab tuaj yeem tsim cov tshuaj los ntawm milligrams mus rau tons hauv nplai, thiab ua raws li ISO 9001 cov qauv thiab cov khoom tshwj xeeb GMP.