7,8-Dihydroxyflavone (7,8-DHF) yog ib qho tshwm sim ntawm flavonoid uas qhia tau hais tias kev cog lus hauv ntau qhov chaw ntawm kev noj qab haus huv. Yog tias koj txaus siab rau cov khoom siv ntuj tsim los yog cov khoom noj khoom haus uas yuav pab txhawb lub hlwb kev noj qab haus huv, kev xav, thiab kev noj qab haus huv tag nrho, 7,8-DHF yuav tsim nyog tshawb nrhiav. Lub 7,8-Dihydroxyflavone Powder muab los ntawm Suzhou Myland muaj tus lej CAS ntawm 38183-03-8 thiab purity txog li 98%. Cov khoom tau dhau los ua kev tswj hwm nruj thiab ua raws li cov qauv thoob ntiaj teb, ua kom cov khoom siv tau zoo thiab kev nyab xeeb ntawm cov khoom. , tsim nyog rau kev tshawb fawb, kev tsim tshuaj, kev kho mob cov khoom tsim thiab lwm yam kev lag luam, muab kev xaiv zoo rau koj.
Tom ntej: 7,8-Dihydroxyflavone (7,8-DHF)yog ib qho tsis tshua muaj flavonoid compound ib txwm tshwm sim hauv qhov xwm txheej. Nws tau raug kuaj pom hauv Astragalus pumila, Primula grandifolia thiab Hubei crabapple. tau tshwm sim raws li kev cog lus nootropic compound. Nws tau pom ntau yam ntawm cov teebmeem neuropharmacological hauv kev tshawb fawb preclinical,
Flavonoids yog ib chav kawm ntawm polyphenolic compounds pom nyob rau hauv ntau yam txiv hmab txiv ntoo, zaub, thiab lwm yam nroj tsuag. Nyob rau hauv xyoo tas los no, lawv tau txais kev saib xyuas ntau heev vim lawv cov tshuaj tua kab mob antioxidant, tiv thaiv kab mob, thiab cov khoom tiv thaiv neuroprotective.
Cov tebchaw no tau pom tias muaj txiaj ntsig zoo rau lub hlwb, nrog rau kev txhim kho kev txawj ntse thiab tiv thaiv cov kab mob neurodegenerative. 7,8-DHF yog ib qho tseem ceeb tshaj plaws polyphenolic tebchaw uas tau txais kev saib xyuas raws li nootropic. Nws tau raug kawm txog nws cov txiaj ntsig zoo ntawm kev xav, nco, kev kawm, kev ntxhov siab, thiab lwm yam kev paub txog kev paub.
Cov teebmeem neurological ntawm 7,8-DHF tau xav tias yuav tsum tau kho los ntawm nws cov kev cuam tshuam nrog cov receptors tshwj xeeb. Nws tau raug pom tias yog TrkA, ib qho receptor koom nrog hauv cov paj hlwb kev loj hlob ntawm qhov taw qhia thiab tseem ceeb rau kev muaj sia nyob neuronal thiab plasticity.
7,8-DHF ua los ntawm kev tswj cov kev qhia ntawm ntau yam receptors, suav nrog glutamate receptor subunits thiab BDNF. Nws kuj cuam tshuam rau kev tsim synapse, lub zog metabolism, thiab tso tawm acetylcholine hauv qee qhov chaw hauv lub hlwb.
Tsis tas li ntawd, osteoporosis yog hu ua "tus neeg tua neeg uas ntsiag to" ntawm tib neeg lub cev, ua rau muaj kev hem thawj rau kev noj qab haus huv ntawm cov neeg laus thiab cov laus, tshwj xeeb tshaj yog cov poj niam postmenopausal. Nyob rau hauv ib txwm physiological tej yam kev mob, pob txha remodeling nyob rau hauv ib tug balanced lub xeev; tab sis thaum muaj qhov tsis txaus ntseeg ntawm cov pob txha osteoblast-mediated pob txha tsim thiab osteoclast-mediated pob txha resorption, thiab cov pob txha tsim tsis txaus los ntxiv cov pob txha absorbed, pob txha loj yuav txo. , microstructure ntawm pob txha cov ntaub so ntswg raug puas tsuaj, ua rau osteoporosis.
7,8-Dihydroxyflavone (7,8-DHF) yog cov nroj tsuag-derived flavonoid uas tuaj yeem ua raws li kev ua haujlwm ntawm lub hlwb-derived neurotrophic factor (BDNF), induce dimerization ntawm TrkB receptors thiab qhib nws downstream signaling molecules. Cov kev tshawb fawb tau pom tias BDNF tuaj yeem txhawb kev sib txawv ntawm osteoblast thiab tsiv teb tsaws thiab ua kom cov pob txha zoo.
7,8-DHF tuaj yeem txhawb nqa kev loj hlob thiab kev sib txawv ntawm osteoblasts los ntawm kev cuam tshuam nrog TrkB thiab ua kom Wnt / β-catenin signaling txoj hauv kev, thiab tuaj yeem cuam tshuam cov tiam ntawm osteoclasts los ntawm kev txo qis qhov kev hloov pauv c-fos; Tsis tas li ntawd, 7 ,8-DHF tuaj yeem txhim kho cov osteoporosis phenotype hauv ovariectomized nas.
Cov qauv tshuaj thiab cov khoom ntawm 7,8-dihydroxyflavone
Nws muaj ob pawg hydroxyl ntawm lub nplhaib benzene thiab ib pawg hydroxyl ntawm lub nplhaib pyrrolone. Cia peb saib ze dua ntawm cov qauv tshuaj ntawm 7,8-dihydroxyflavone:
Cov mis mos molecular ntawm 7,8-DHF yog C15H10O5, qhia tias nws muaj 15 carbon atoms, 10 hydrogen atoms, thiab 5 oxygen atoms.
7,8-Dihydroxyflavone yog daj crystalline khoom nrog ib qho hnyav molecular ntawm 286.24 g / mol. Nws yog me ntsis soluble hauv dej vim muaj ntau pawg hydroxyl uas tuaj yeem khi hydrogen rau cov dej molecules.
7,8-DHF mechanism ntawm kev txiav txim: BDNF kev cai thiab Trkb receptor activation
Hais txog cov txheej txheem ntawm kev ua, 7,8-DHF paub los txhawb kev tsim cov BDNF (lub hlwb-derived neurotrophic yam) los ntawm kev khi rau thiab ua kom nws cov receptor TrkB. Tsis tau txais kev paub dhau los, qhov no ua rau muaj kev cuam tshuam ntawm cov kev ua haujlwm ntawm tes uas muaj txiaj ntsig zoo hauv kev tswj hwm kev ua haujlwm zoo neuronal thiab txhawb nqa neurogenesis.
Cia peb saib ze dua ntawm 7,8-DHF lub ntsiab ntawm kev ua hauv qab no.
Brain-derived neurotrophic factor (BDNF) thiab nws lub luag haujlwm hauv neuroplasticity
Nrog rau kev tshawb pom tias lub paj hlwb-derived neurotrophic factor (BDNF) qhia tau txo qis hauv cov kab mob neurodegenerative, tshwj xeeb yog Alzheimer's disease (AD), nws qhov tseem ceeb hauv kev tswj hwm thiab txhim kho lub hlwb kev noj qab haus huv tau dhau los ua pom tseeb. .
BDNF yog qhov tseem ceeb rau ntau yam kev ua haujlwm ntawm lub paj hlwb vim nws txhawb kev sib kis ntawm synaptic, synaptogenesis, thiab synaptic plasticity los ntawm kev taw qhia nrog TrkB receptors. Qhov no ua rau BDNF-TrkB taw qhia txoj hauv kev yog lub hom phiaj zoo rau kev txhim kho cov kev pabcuam kho mob txhawm rau tiv thaiv cov kab mob neurodegenerative.
Cov kev tshawb fawb tsis ntev los no tau delved rau hauv cov txiaj ntsig muaj peev xwm ntawm cov molecule TrkB agonist 7,8-dihydroxyflavone (7,8-DHF) hauv kev txo cov teebmeem thaum ntxov ntawm AD-txog pathology. Hauv kev tshawb fawb ntawm 5xFAD nas qauv ntawm AD, nas tau kho nrog 7,8-DHF rau ob lub hlis pib thaum muaj hnub nyoog ib hlis.
Cov txiaj ntsig ntawm qhov kev tshawb nrhiav no qhia txog kev kho mob muaj peev xwm ntawm 7,8-DHF hauv kev hais txog AD-txog kev hloov pauv neurochemical thiab cov cim kab mob. Qhov tseem ceeb, 7,8-DHF kev kho mob ua rau txo qis cortical Aβ plaque deposition, ib qho tseem ceeb ntawm AD.
Tsis tas li ntawd, nws tiv thaiv cortical neurons los ntawm kev txo qis hauv dendritic arbor complexity, pab tswj tag nrho cov qauv neuronal. Txawm li cas los xij, nws tsis cuam tshuam rau dendritic spine ceev.
Raws li Aytan, Nurgul thiab lwm tus, cov kev kho mob kuj tau pom cov teebmeem neuroprotective hauv hippocampus, tiv thaiv kom nce qib ntawm choline-muaj cov sib txuas thiab txo qis glutamate poob.
Tropomyosin receptor kinase B (Trkb) receptor signaling txoj kev
Xyoo 2010, pawg xibfwb Ye Keqiang ntawm Emory University tau tshaj tawm thawj zaug hauv Kev Ua Haujlwm ntawm National Academy of Sciences (PNAS) tias 7,8-DHF tuaj yeem siv los ua ib qho me me molecule agonist ntawm tropomyosin receptor kinase B ( TrkB), uas tuaj yeem simulate Kev ua haujlwm ntawm lub hlwb-derived neurotrophic yam (BDNF) txuas ntxiv ua kom pom cov kev taw qhia hauv qab ntawm TrkB, xws li MAPK / ERK, PI3K / Akt thiab PKC. Ntxiv mus, cov kev tshawb fawb tom qab pom tau tias 7,8-DHF tuaj yeem txo cov rog rog ntau vim kev rog rog hauv cov poj niam nas los ntawm kev ua kom cov leeg pob txha TrkB, qhia txog kev sib txawv ntawm poj niam txiv neej.
Brain-derived neurotrophic factor (BDNF) tuaj yeem txhawb kev sib txawv ntawm osteoblast, tsiv teb tsaws thiab kho pob txha. BDNF yog ib tug tswv cuab ntawm tsev neeg neurotrophic thiab tswj ntau yam kev lom neeg feem ntau los ntawm kev khi rau transmembrane receptor tyrosine kinase B (TrkB). Txawm li cas los xij, BDNF-induced TrkB teeb liab tau hloov pauv ntawm 10 min thiab peaked ntawm 60 min. Txawm li cas los xij, BDNF muaj ib nrab-lub neej luv luv thiab tsis tuaj yeem hla cov ntshav-hlwb teeb meem.
7,8-dihydroxyflavone (7,8-DHF) yog cov nroj tsuag-derived flavonoid uas muaj peev xwm kov yeej cov kev txwv saum toj no ntawm BDNF thiab tau txheeb xyuas tias ua haujlwm zoo BDNF mimetic thiab tam sim no siv rau hauv ntau yam biochemical thiab cellular systems. Nws tuaj yeem ua rau TrkB dimerization thiab qhib nws cov lus qhia qis qis.
tropomyosin receptor kinase B (TrkB) receptor plays lub luag haujlwm tseem ceeb hauv kev kho cov teebmeem ntawm BDNF ntawm cov neurons. Raws li ib tug transmembrane tyrosine kinase receptor, TrkB yog thawj receptor rau BDNF thiab pib ib tug cascade ntawm intracellular signaling txheej xwm raws li khi rau neurotrophic yam.
BDNF ua kom TrkB ua rau muaj ntau txoj hauv kev tseem ceeb hauv lub cev, suav nrog phosphatidylinositol 3-kinase (PI3K)-Akt, mitogen-activated protein kinase (MAPK)-extracellular signal-regulated kinase (ERK), thiab phospholipase Cγ (PLCγ)-protein. PKC) txoj kev. Txhua txoj hauv kev no ua rau muaj qhov sib txawv ntawm kev ua haujlwm neuronal thiab kev noj qab haus huv.
Txoj hauv kev PI3K-Akt yog qhov tseem ceeb rau kev txhawb nqa kev muaj sia nyob ntawm neuronal thiab inhibiting apoptosis. BDNF-TrkB signaling ua rau txoj hauv kev no kom muaj sia nyob ntawm tes los ntawm inhibiting pro-apoptotic yam thiab stimulating anti-apoptotic yam, yog li ua kom muaj kev ruaj ntseg ntawm cov neurons noj qab haus huv.
Ntawm qhov tod tes, txoj hauv kev MAPK-ERK plays lub luag haujlwm tseem ceeb hauv kev sib txawv neuronal thiab kev loj hlob. BDNF-TrkB signaling txhawb kev ua haujlwm ntawm MAPK-ERK txoj hauv kev, uas nyob rau hauv lem txhawb neuronal maturation thiab sib txawv thiab lawv kev koom ua ke rau hauv cov network neuronal uas twb muaj lawm.
Txoj hauv kev PLCγ-PKC yog qhov tseem ceeb rau kev tswj cov khoom siv hluavtaws, cov txheej txheem tseem ceeb ntawm kev kawm thiab kev nco. BDNF-TrkB signaling modulates cov haujlwm ntawm txoj kev no, thaum kawg ua rau muaj kev hloov pauv hauv synaptic zog thiab kev sib txuas.
Qhov kev hloov pauv no txhawb kev hloov pauv thiab rov tsim kho ntawm neural circuits hauv kev teb rau cov kev paub tshiab thiab ib puag ncig stimuli.
Neuroprotective zog
Kev tshawb fawb qhia tau hais tias qhov no flavonoid tiv thaiv neurons los ntawm oxidative kev nyuaj siab thiab apoptosis (programmed cell tuag). Oxidative stress yog ib qho tseem ceeb hauv cov kab mob neurodegenerative xws li Alzheimer's thiab Parkinson's disease. Los ntawm kev tshem tawm cov dawb radicals thiab txo cov oxidative puas tsuaj, 7,8-DHF tuaj yeem pab tiv thaiv kev ncaj ncees thiab kev ua haujlwm.
Hauv kev tshawb fawb tsiaj, 7,8-DHF tau pom tias txhim kho kev txawj ntse thiab kev nco. Piv txwv li, hauv cov qauv ntawm Alzheimer's disease, 7,8-DHF tau pom tias yuav txhim kho synaptic plasticity, uas yog qhov tseem ceeb rau kev kawm thiab kev nco. Mechanism ntawm kev ua
Anti-inflammatory nyhuv
Ntxiv nrog rau nws cov khoom tiv thaiv neuroprotective, 7,8-dihydroxyflavone kuj muaj cov tshuaj tiv thaiv kab mob. Kev mob ntev yog ib qho ntawm ntau yam kab mob, nrog rau cov kab mob neurodegenerative. Los ntawm kev hloov kho txoj hauv kev, 7,8-DHF tuaj yeem pab txo qis neuroinflamation, uas feem ntau cuam tshuam nrog kev paub tsis meej.
Antioxidant zog: ROS scavenging thiab lipid peroxidation
7,8-DHF muaj antioxidant zog raws li muaj pov thawj los ntawm nws lub peev xwm mus khawb reactive oxygen hom (ROS) thiab txo lipid peroxidation. Cov teebmeem no pab txhawb rau nws cov teebmeem neuroprotective los ntawm alleviating oxidative stress-induced neuronal puas thiab tsis ua haujlwm.
Cov kev tshawb fawb pom tau hais tias 7,8-DHF inhibits zus tau tej cov pro-inflammatory cytokines thiab txo cov kev ua ntawm microglia, lub cev tsis muaj zog nyob rau hauv lub hauv paus paj hlwb. Qhov kev tiv thaiv kab mob no tsis yog tsuas yog tiv thaiv cov neurons nkaus xwb tab sis kuj tsim ib qho chaw zoo dua rau kev paub txog kev ua haujlwm.
Muab nws cov txiaj ntsig zoo rau lub hlwb kev noj qab haus huv, 7,8-dihydroxyflavone muaj peev xwm siv tau rau ntau yam kev noj qab haus huv thiab tshuaj. Qee cov npe nrov tshaj plaws suav nrog:
Memory consolidation thiab retrieval
7,8-DHF tau pom los txhim kho kev nco sib koom ua ke thiab rov qab los ntawm ntau yam hippocampal-nyob ntawm kev kawm thiab kev nco ua haujlwm hauv cov qauv nas. Cov kev tshawb pom no qhia tias 7,8-DHF tej zaum yuav yog ib qho kev cog lus nootropic rau kev txhim kho kev nco hauv ob tus neeg noj qab haus huv thiab cov neeg uas muaj kev nco tsis zoo.
Synaptic plasticity: lub sij hawm ntev potentiation thiab kev nyuaj siab
Raws li tau hais dhau los, 7,8-DHF tau pom tias yuav hloov kho synaptic plasticity los ntawm kev txhawb nqa LTP thiab txo LTD hauv hippocampus. Cov teebmeem no tau xav tias yuav tsum tau kho los ntawm nws lub peev xwm los qhib TrkB receptors thiab tom qab ntawd txhim kho BDNF txoj kev taw qhia.
Qhov kev hloov pauv ntawm synaptic plasticity no ua rau muaj kev txhim kho hauv kev paub txog kev ua haujlwm raws li kev tswj hwm 7,8-DHF.
Kev paub txog kev txawj ntse
Raws li tau hais dhau los, 7,8-DHF qhia tau tias muaj peev xwm txhim kho kev txawj ntse thiab kev nco. Qhov no ua rau nws yog ib tus neeg sib tw rau cov tshuaj pab txhawm rau txhim kho kev puas siab puas ntsws, tshwj xeeb tshaj yog nyob rau hauv cov neeg laus lossis cov neeg uas muaj kev txawj ntse poob.
Absorption, Distribution, Metabolism, and Excretion (ADME): 7,8-DHF nthuav tawm cov khoom siv tshuaj muaj txiaj ntsig zoo, suav nrog kev nqus sai, kev faib tawm dav, thiab kev nkag mus rau lub hlwb. Nws yog feem ntau metabolized los ntawm daim siab, nrog rau feem ntau ntawm cov compound tawm hauv cov quav thiab ib qho me me tawm hauv cov zis.
Ntshav-hlwb barrier permeability thiab hlwb permeability. Ib qho ntawm cov yam ntxwv tseem ceeb ntawm 7,8-DHFyog nws muaj peev xwm hla cov ntshav-hlwb barrier (BBB) thiab nkag mus rau lub hlwb cov ntaub so ntswg, uas yog ib qho tseem ceeb rau nws cov kev ua tau zoo raws li ib tug nootropic.
Preclinical Safety Profile - Kev Tshawb Fawb Txog Kev Tiv Thaiv Kab Mob thiab Mob Ntev: Kev tshawb fawb txog kev nyab xeeb ua ntej pom tau tias 7,8-DHF muaj qhov kev nyab xeeb zoo, tsis muaj qhov cuam tshuam loj heev tau pom nyob rau hauv kev mob toxicity kev tshawb fawb hauv cov nas. Txawm li cas los xij, kev ntsuas kev nyab xeeb ntxiv, suav nrog cov kev tshawb fawb hauv cov tsiaj siab dua thiab tib neeg cov ntsiab lus, yuav tsum txiav txim siab nws txoj kev nyab xeeb rau kev siv tshuaj kho mob.
Txawm hais tias cov kev tshawb fawb hauv tsev kho mob tau pom tias 7,8-DHF muaj qhov pom zoo rau kev nyab xeeb, cov kev mob tshwm sim tuaj yeem tshwm sim hauv tib neeg cov kev kawm tseem tsis paub ntau. Raws li nrog txhua qhov sib xyaw tshiab, kev ceev faj yuav tsum tau siv thiab muaj peev xwm saib xyuas qhov tshwm sim thaum ntsuas nws siv rau tib neeg.
Nyob ntawm 7,8-DHF cov txheej txheem ntawm kev ua thiab cov teebmeem ntawm TrkB receptors, qee qhov kev mob tshwm sim uas yuav cuam tshuam nrog 7,8-DHF yuav suav nrog:
Mob taub hau: BDNF thiab TrkB receptor activation tswj kev ua haujlwm neuronal thiab excitability; kev tswj hwm ntawm 7,8-DHF tuaj yeem ua rau mob taub hau rau qee tus neeg.
Insomnia: Ua kom muaj kev ua haujlwm neuronal thiab synaptic plasticity tuaj yeem cuam tshuam rau cov qauv kev pw tsaug zog, uas ua rau insomnia lossis pw tsaug zog cuam tshuam.
Cov teeb meem hauv plab hnyuv: Zoo li ntau cov tshuaj bioactive, 7,8-DHF tuaj yeem ua rau mob plab hnyuv, xws li xeev siab, ntuav, lossis raws plab hauv qee tus neeg.
Nws yog ib qho tseem ceeb kom nco ntsoov tias cov kev mob tshwm sim no yuav tsum tau kawm ntxiv hauv kev sim tshuaj. Muab nws lub peev xwm los hloov kho BDNF signaling thiab TrkB receptor activation, yuav tsum tau ceev faj thaum sib txuas 7,8-DHF nrog lwm cov tshuaj uas tsom rau txoj hauv kev no lossis muaj cov txheej txheem zoo sib xws.
Raws li ib qho tseem ceeb compound, 7,8-Dihydroxyflavone tau nyiam heev vim nws cov kev ua ub no lom neeg. Rau cov kws tshawb fawb thiab kev lag luam, nws yog ib qho tseem ceeb kom nrhiav tau cov khoom zoo 7,8-Dihydroxyflavone Powder. Lub 7,8-Dihydroxyflavone Powder muab los ntawm Suzhou Myland muaj tus lej CAS ntawm 38183-03-8 thiab purity txog li 98%. Cov khoom tau dhau los ua kev tswj hwm nruj thiab ua raws li cov qauv thoob ntiaj teb, ua kom cov khoom siv tau zoo thiab kev nyab xeeb ntawm cov khoom. , tsim nyog rau kev tshawb fawb, kev tsim tshuaj, kev kho mob cov khoom tsim thiab lwm yam kev lag luam, muab kev xaiv zoo rau koj.
Kev ruaj ntseg zoo
Peb paub tias qhov zoo ntawm peb cov khoom ncaj qha cuam tshuam rau peb cov neeg siv khoom kev tshawb fawb thiab cov txiaj ntsig ntawm daim ntawv thov. Yog li ntawd, Suzhou Myland nruj me ntsis raws li GMP (Good Manufacturing Practice) thiab ISO certification cov txheej txheem thaum lub sij hawm ntau lawm txheej txheem los xyuas kom meej stability thiab sib xws ntawm txhua batch ntawm cov khoom. Tsis tas li ntawd, peb pab pawg R & D tseem ua tiav cov thev naus laus zis tshiab thiab siv zog los txhim kho cov khoom zoo thiab kev ua haujlwm tsis tu ncua.
Kev pabcuam neeg siv khoom
Suzhou Myland tsis yog tsuas yog muab cov khoom lag luam zoo, tab sis kuj them nyiaj rau cov neeg siv khoom xav tau. Peb muaj cov kws tshaj lij kev txhawb nqa pab pawg uas tuaj yeem muab cov neeg siv khoom nrog cov lus qhia siv khoom siv thiab cov lus qhia ua haujlwm los pab cov neeg siv khoom ua tiav cov txiaj ntsig zoo hauv kev tshawb fawb thiab kev thov. Txawm hais tias nws yog kev sim me me lossis kev tsim khoom loj, peb tuaj yeem muab cov kev daws teeb meem hloov tau raws li qhov xav tau ntawm cov neeg siv khoom sib txawv.
Yuav Ua Li Cas Tau Txais 7,8-Dihydroxyflavone Powder
Yog tias koj tab tom nrhiav kom zoo 7,8-Dihydroxyflavone Powder, Suzhou Myland yog koj qhov kev xaiv zoo tshaj plaws. Koj tuaj yeem tiv tauj peb ntawm:
Lub vev xaib raug cai: Mus saib lub vev xaib raug cai ntawm Suzhou Myland kom paub ntau ntxiv txog cov ntaub ntawv khoom thiab kev txhawb nqa.
Kev sib tham hauv online: Sib txuas lus ncaj qha nrog peb pab neeg muab kev pabcuam los ntawm kev sib tham hauv online uas muab los ntawm lub vev xaib kom tau txais cov ntaub ntawv khoom thiab cov lus hais uas koj xav tau.
Kev sib cuag hauv xov tooj: Hu rau peb tus lej xov tooj kom sib txuas lus nrog cov neeg ua haujlwm muag khoom thiab tau txais cov ncauj lus kom ntxaws txog cov khoom lag luam thiab cov lus qhia yuav khoom.
Email nug: Koj tuaj yeem nug peb cov ntaub ntawv khoom ntawm email, thiab peb yuav teb koj sai li sai tau.
Hauv kev xaus
Raws li ib qho tseem ceeb compound nrog ntau yam kev ua ub no, 7,8-Dihydroxyflavone maj mam dhau los ua ib qho tseem ceeb hauv kev tshawb fawb thiab kev siv hauv kev lag luam. Lub siab-purity 7,8-Dihydroxyflavone Powder muab los ntawm Suzhou Myland yuav muab kev txhawb zog rau koj cov kev tshawb fawb thiab kev tsim khoom nrog nws cov kev pabcuam zoo thiab txhim khu kev qha. Peb tos ntsoov yuav ua haujlwm nrog koj los tshawb nrhiav ntau daim ntawv thov muaj peev xwm ntawm 7,8-Dihydroxyflavone.
Q: 7,8-dihydroxyflavone yog dab tsi?
A: 7,8-Dihydroxyflavone yog ib txwm tshwm sim flavonoid paub txog nws cov peev xwm tiv thaiv kab mob neuroprotective thiab tab tom kawm txog nws cov teebmeem ntawm kev txawj ntse thiab kev zoo siab.
Q: Cov txiaj ntsig zoo ntawm 7,8-dihydroxyflavone yog dab tsi?
A: Kev tshawb fawb qhia tau tias 7,8-dihydroxyflavone tuaj yeem pab txhim kho kev nco, txo kev ntxhov siab, thiab tiv thaiv kab mob neurodegenerative. Nws cov khoom antioxidant kuj tseem tuaj yeem txhawb kev noj qab haus huv tag nrho los ntawm kev tawm tsam oxidative kev nyuaj siab.
Q: Dab tsi yog bioavailability ntawm 7,8-DHF?
A: Lub bioavailability ntawm 7,8-dihydroxyflavone (7,8-DHF) hauv kev tshawb fawb tsiaj yog kwv yees li 5% (hauv nas) vim nws cov dej tsis zoo thiab cov metabolism sai. Txawm hais tias nws tsis muaj bioavailability, 7,8-DHF tseem tuaj yeem hla cov hlab ntsha-hlwb thiab cuam tshuam rau lub hlwb. Kev tshawb fawb ntxiv yog xav tau los txiav txim siab nws bioavailability hauv tib neeg thiab tshawb nrhiav txoj hauv kev los txhim kho nws.
Q: 7,8-DHF ua rau koj xav li cas?
A: Raws li nootropic, 7,8-dihydroxyflavone (7,8-DHF) muaj txiaj ntsig zoo rau kev paub txog kev ua haujlwm thiab lub siab xav. Cov tib neeg muaj kev nco zoo dua, ua kom pom tseeb, thiab muaj peev xwm kawm tau zoo dua.
Kev lees paub: Kab lus no yog rau cov ntaub ntawv dav dav nkaus xwb thiab yuav tsum tsis txhob raug txhais raws li cov lus qhia kho mob. Qee cov ntaub ntawv blog tshaj tawm los ntawm Is Taws Nem thiab tsis yog kev tshaj lij. Lub vev xaib no tsuas yog lub luag haujlwm rau kev txheeb xyuas, formatting thiab kho cov ntawv. Lub hom phiaj ntawm kev xa cov ntaub ntawv ntau ntxiv tsis txhais tau hais tias koj pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Nco ntsoov sab laj nrog tus kws kho mob ua ntej siv cov tshuaj ntxiv lossis hloov pauv koj txoj kev kho mob.
Post lub sij hawm: Oct-14-2024
