O-304 CAS No.:1261289-04-6 Tsim cov leeg nqaij thiab poob rog.
Cov Khoom Siv
| Lub npe khoom | O-304 |
| Lwm lub npe | 4-Chloro-N-[2-[(4-chlorophenyl)methyl]-2,3-dihydro-3-oxo-1,2,4-thiadiazol-5-yl]benzamide |
| CAS Nr. | 1261289-04-6 |
| Cov mis molecular | C16H11Cl2N3O2S |
| Qhov hnyav ntawm cov molecule | 380.25 |
| Kev dawb huv | 98% |
| Qhov tsos | Dawb rau cov hmoov dawb dawb |
| Ntim khoom | 1kg/hnab, 25kg/phaj |
| Daim Ntawv Thov | Khoom Noj Khoom Haus Ntxiv Raw Khoom |
Kev taw qhia txog khoom
O-304 yog ib qho tshuaj AMPK me me uas ua rau AMPK ua haujlwm zoo dua los ntawm kev txwv tsis pub phosphorylation ntawm phosphorylated AMPK (pAMPK), yog li ua rau cov pAMPK ntau ntxiv yam tsis txo cov adenosine triphosphate (ATP) hauv cov hlwb. Nws muaj ntau txoj hauv kev ua haujlwm, suav nrog kev txhim kho cov metabolism ntawm cov piam thaj, txo cov tshuaj insulin tsis kam, thiab tiv thaiv cov kab mob plawv.
Feature
(1) Kev ntshiab siab: O-304 yog tsim los ntawm cov txheej txheem tsim khoom zoo, ua tiav cov khoom ntshiab siab. Kev ntshiab siab txhais tau tias muaj kev nyab xeeb zoo dua.
(2) Kev Ua Haujlwm ntawm Lub Cev:O-304 yog ib qho tshuaj uas ua rau AMPK (AMP-activated protein kinase) ua haujlwm thaum noj. Nws ua rau AMPK ua haujlwm ntau dua los ntawm kev txwv tsis pub pAMPK dephosphorylation.
Cov ntawv thov
1. Kev Ua Haujlwm AMPK: O-304 ua rau AMPK ua haujlwm ntau ntxiv los ntawm kev txwv tsis pub cov txheej txheem dephosphorylation ntawm phosphorylated AMPK (pAMPK), yog li tswj kev sib npaug ntawm lub zog metabolism.
2. Txhim kho kev zom zaub mov qab zib: Hauv kev tshawb fawb txog tsiaj, ib koob tshuaj ntawm 100 mg / kg ntawm O-304 tau pab tswj kom cov ntshav qab zib thiab cov insulin hauv cov ntshav ruaj khov, txo qhov hnyav ntawm kev zom zaub mov uas tshwm sim los ntawm kev noj zaub mov uas muaj roj ntau, thiab tiv thaiv kev hloov pauv ntawm cov ntshav qab zib thiab kev nce insulin tsis zoo uas tshwm sim los ntawm kev noj zaub mov tsis sib npaug.
3. Ptiv thaiv cov hlab ntsha elasticity:O-304 pab tswj cov ntshav siab kom nyob rau theem noj qab nyob zoo, txo kev ntxhov siab rau cov hlab ntsha, thiab muab kev tiv thaiv mus sij hawm ntev rau cov kab mob plawv thiab cov hlab ntsha hauv lub hlwb, txhawb kev ruaj ntseg ntawm lub siab thiab lub zog ruaj khov.
4.Txhawb kom cov hluas nyob ntev:O-304 tsom mus rau txoj kev teeb liab AMPK-mTOR, tswj hwm cov txheej txheem ntawm cellular autophagy, txhawb kev catabolism ntawm cov protein laus thiab cov lipids tsis zoo, thiab tswj hwm ib puag ncig cellular huv si thiab muaj zog, yog li ntawd ncua kev laus ntawm cellular.
