Oleoylethanolamide (OEA) hmoov chaw tsim tshuaj paus CAS No.: 111-58-0 98%, 85% purity min. rau cov khoom xyaw ntxiv
Khoom Parameters
| Khoom npe | Oleoyl ethanolamide |
| Lwm lub npe | N-oleoyl ethanolamine; N-(2-hydroxyethyl)-,(Z)-9-Octadecenamide |
| CAS Nr. | 111-58-0 |
| Cov mis mos molecular | C20H39NO2 |
| Molecular hnyav | 325.53 Nws |
| Purity | 98.0%, 85.0% |
| Qhov tshwm sim | Fine dawb crystal hmoov |
| Ntim | 1kg / hnab, 25kg / nruas |
| Daim ntawv thov | Mob nyem, anti-inflammatory |
Khoom taw qhia
Oleoylethanolamide yog ib qho chaw nruab nrab amide uas muaj lipophilic oleic acid thiab hydrophilic ethanolamine. Oleoylethanolamide kuj yog ib qho tshwm sim lipid molecule hauv lwm cov tsiaj thiab cov ntaub so ntswg. Nws yog dav nyob rau hauv cov tsiaj thiab cov ntaub so ntswg xws li cocoa hmoov, soybeans, thiab txiv ntseej, tab sis nws cov ntsiab lus tsis tshua muaj heev. Tsuas yog thaum ib puag ncig sab nraud hloov pauv lossis cov zaub mov raug txhawb nqa, lub cev cov ntaub so ntswg ntawm tes tsuas yog tom qab ntawd yuav tsim cov tshuaj no ntau dua.
Nyob rau hauv chav tsev kub, Oleoylethanolamide yog cov khoom dawb nrog lub melting point ntawm txog 50 ° C. Nws yog yooj yim soluble nyob rau hauv cawv kuab tshuaj xws li methanol thiab ethanol, yooj yim soluble nyob rau hauv non-polar solvents xws li n-hexane thiab ether, thiab insoluble nyob rau hauv dej. OEA yog ib qho amphiphilic molecule ib txwm siv los ua surfactant thiab xab npum hauv kev lag luam tshuaj. Txawm li cas los xij, kev tshawb fawb ntxiv tau pom tias OEA tuaj yeem ua lub luag haujlwm lipid signaling molecule nyob rau hauv lub plab-hlwb axis thiab tso tawm ntau cov haujlwm lom hauv lub cev, suav nrog: tswj kev qab los noj mov, txhim kho lipid metabolism, txhim kho kev nco thiab kev paub thiab lwm yam haujlwm. Ntawm lawv, Oleoylethanolamide lub luag haujlwm ntawm kev tswj kev qab los noj mov thiab txhim kho lipid metabolism tau txais kev mloog zoo tshaj.
Oleoylethanolamide tuaj yeem tswj hwm kev noj zaub mov thiab lub zog homeostasis los ntawm kev ua kom peroxisome proliferator-activated receptor-α. Tsis tas li ntawd, Oleoylethanolamide nthuav tawm lwm cov haujlwm ntsig txog kev noj qab haus huv, suav nrog kev hloov pauv hloov pauv kev ua haujlwm hauv lysosomal-rau-nuclear signaling txoj hauv kev cuam tshuam nrog kev tswj kav ntev thiab tiv thaiv cov hlab ntsha uas tswj kev ntxhov siab. Kev tshawb fawb tseem qhia tias Oleoylethanolamide tuaj yeem muaj cov teebmeem neuroprotective. Hauv cov qauv tsiaj, nws tau pom tias txo kev puas tsuaj los ntawm kev mob stroke thiab kev puas hlwb puas tsuaj. Kev tswj hwm cov nyhuv ntawm Oleoylethanolamide yog ntaus nqi los ntawm nws txoj kev khi rau PPARα, uas dimerizes nrog retinoid X receptor (RXR) thiab ua kom nws ua lub zog muaj zog cuam tshuam nrog kev sib koom ua ke ntawm lub zog homeostasis, lipid metabolism, autophagy, thiab o. downstream lub hom phiaj.
Feature
(1) Cov purity siab: OEA tuaj yeem tau txais cov khoom siv purity siab los ntawm cov txheej txheem ntau lawm. High purity txhais tau hais tias bioavailability zoo dua thiab tsawg dua qhov tsis zoo.
(2) Kev Nyab Xeeb: OEA tau raug pov thawj tias muaj kev nyab xeeb rau tib neeg lub cev.
(3) Kev ruaj ntseg: OEA muaj kev ruaj ntseg zoo thiab tuaj yeem tswj hwm nws cov haujlwm thiab cov txiaj ntsig hauv qhov chaw sib txawv thiab chaw cia khoom.
(4) Yooj yim rau nqus: OEA tuaj yeem nqus tau sai los ntawm tib neeg lub cev thiab muab faib rau cov ntaub so ntswg thiab kabmob sib txawv.
Daim ntawv thov
Oleoylethanolamide yog lub ntuj ethanolamide lipid siv los ua kev npaj noj haus thiab lub cev qhov hnyav hauv ntau hom kab mob vertebrate. Nws yog ib qho metabolite ntawm oleic acid tsim nyob rau hauv tib neeg txoj hnyuv. Oleylethanolamide (OEA) yog ib qho molecule uas tswj cov lipid metabolism thiab lub zog homeostasis. Nws lo rau PPAR Alpha receptors thiab pab tswj plaub yam: kev tshaib kev nqhis, lub cev rog, roj cholesterol thiab qhov hnyav. PPAR Alpha sawv cev rau peroxide proliferator-activated receptor alpha, thiab bioactive lipid amide oleoylethanolamide (OEA) muaj ntau yam khoom tshwj xeeb hauv tsev, suav nrog kev ua haujlwm tiv thaiv kab mob, kev tiv thaiv kab mob tiv thaiv kab mob, thiab tshuaj tiv thaiv antioxidant.
