CMS121 hmoov chaw tsim tshuaj paus CAS No.: 1353224-53-9 98.0% purity min. rau cov khoom xyaw ntxiv
Khoom Parameters
| Khoom npe | CMS121 |
| Lwm lub npe | CMS-121; 1,2-Benzenediol,4-[4-(cyclopentyloxy)-2-quinolinyl]-; 4-(4-(cyclopentyloxy)quinolin-2-yl)benzene-1,2-diol(CMS121); ACC, AcetylCoenzymeACarboxylase, kab mob, neuroprotective, inhibit, anti-inflammatory, mitochondrial, Alzheimer's, antioxidative, acetylation, Inhibitor, H3K9, Acetyl-CoACarboxylase, CMS121, dementia, ACC1, CMS-121 |
| CAS Nr. | 1353224-53-9 |
| Cov mis mos molecular | C20H19NO3 |
| Molecular hnyav | 321.37 Nws |
| Purity | 98.0% |
| Qhov tshwm sim | Lub teeb daj hmoov |
| Daim ntawv thov | Khoom noj khoom haus ntxiv Raw Khoom |
Khoom taw qhia
4-(4-(cyclopentyloxy)quinolin-2-yl)benzene-1,2-diol yog ib qho chaw hu ua CMS121. Cov txheej txheem complexity qhia tias nws yuav muaj cov khoom tshwj xeeb thiab muaj peev xwm siv tau. Txhawm rau nkag siab nws qhov tseem ceeb, nws pab txheeb xyuas cov pab pawg ua haujlwm tam sim no thiab txheeb xyuas lawv qhov cuam tshuam. Lub xub ntiag ntawm lub nplhaib quinoline qhia tau hais tias qhov sib xyaw ua ke tuaj yeem ua haujlwm lom neeg. Quinoline-derived molecules paub txog lawv cov khoom siv lom neeg sib txawv, suav nrog kev ua haujlwm tiv thaiv kab mob thiab tiv thaiv kab mob. Kev sib txuas ntawm pawg cyclopentyloxy tuaj yeem ua rau cov solubility ntawm cov khoom sib txuas lossis txhim kho nws cov kev ua haujlwm lom neeg los ntawm cov teebmeem steric. Hauv kev tshawb fawb ntawm HT22 hlwb, CMS-121 tau pom cov teebmeem tseem ceeb hauv neuroprotective, tiv thaiv cov hlwb los ntawm ischemia thiab oxidative puas. Tsis tas li ntawd, CMS-121 muaj cov tshuaj tiv thaiv kab mob tseem ceeb, qhia txog nws lub peev xwm los hloov kho cov lus teb. Los ntawm kev ua li ntawd, CMS-121 muaj peev xwm txo tau qhov mob ntawm ntau yam ntaub so ntswg thiab hauv nruab nrog cev. CMS-121 muaj zog pharmacological ua haujlwm raws li inhibitor ntawm acetyl-CoA carboxylase 1 (ACC1). Nws cov nyhuv inhibitory muaj zog ntawm ACC1 ua rau nws muaj txiaj ntsig zoo.
Feature
(1) Cov purity siab: CMS-121 tuaj yeem tau txais cov khoom lag luam siab huv los ntawm cov txheej txheem ntau lawm. High purity txhais tau hais tias bioavailability zoo dua thiab tsawg dua qhov tsis zoo.
(2) Kev Nyab Xeeb: Kev nyab xeeb siab, tsis tshua muaj tshwm sim.
(3) Kev ruaj ntseg: CMS-121 muaj kev ruaj ntseg zoo thiab tuaj yeem tswj hwm nws cov haujlwm thiab cov txiaj ntsig hauv qhov chaw sib txawv thiab chaw cia khoom.
Daim ntawv thov
CMS-121 yog ib qho quinolone derivative thiab qhov ncauj nquag acetyl-CoA carboxylase 1 (ACC1) inhibitor nrog cov khoom lag luam pheej hmoo. Kev tshawb fawb dav tau ua los tshawb xyuas cov txiaj ntsig zoo ntawm CMS-121 hauv ntau qhov chaw, suav nrog kev tiv thaiv neuroprotection, tiv thaiv kab mob, kev ua haujlwm antioxidant, thiab nws qhov cuam tshuam rau cov cim cuam tshuam nrog kev laus noj qab haus huv.
