Chaw tsim tshuaj Lemairamin (WGX-50) hmoov CAS No.: 29946-61-0 98.0% purity min. rau cov khoom xyaw ntxiv
Cov Yeeb Yaj Kiab Txog Khoom
Cov Khoom Siv
| Lub npe khoom | Lemairamin |
| Lwm lub npe | 2-Propenamide, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-, (2E)-; Lemairamin (WGX-50) |
| CAS Nr. | 29946-61-0 |
| Cov mis molecular | C19H21NO3 |
| Qhov hnyav ntawm cov molecule | 311.37 |
| Kev dawb huv | 98.0% |
| Qhov tsos | Dawb rau cov hmoov dawb dawb |
| Daim Ntawv Thov | Khoom Noj Khoom Haus Ntxiv Raw Khoom |
Kev taw qhia txog khoom
Lemairamin lossis Wgx50 yog ib qho tshuaj ntuj uas tau rho tawm los ntawm cov kua txob uas tau pom tias muaj txiaj ntsig zoo hauv kev tiv thaiv kab mob Alzheimer. Cov kev tshawb fawb tau pom tias nws tuaj yeem tiv thaiv Aβ-induced neuronal apoptosis, txo cov neuronal calcium toxicity, thiab txo qhov sib sau ua ke ntawm Aβ oligomers hauv lub cerebral cortex. Tsis tas li ntawd, wgx50 tau pom tias txhim kho kev ua haujlwm ntawm kev paub hauv nas. Kev tshawb fawb qhia tias wgx50 muaj peev xwm tiv thaiv cov protein-protein sib sau ua ke ntawm cov amyloid molecules. Zuag qhia tag nrho, wgx50 muaj peev xwm tiv thaiv kab mob Alzheimer thiab tej zaum yuav muab txoj hauv kev tshiab rau kev tsim cov tshuaj uas tsom mus rau Aβ oligomers. Tsis tas li ntawd, WGX-50 qhia txog kev ua haujlwm tiv thaiv kev o, uas ua rau nws yog tus neeg sib tw zoo rau kev kho cov kab mob o. WGX-50 tau pom tias muaj cov teebmeem tseem ceeb rau daim tawv nqaij, xws li txo cov wrinkles thiab txhim kho daim tawv nqaij elasticity. Ntxiv rau cov tshuaj ntuj uas tau rho tawm los ntawm cov nroj tsuag Zanthoxylum bungeanum, tam sim no muaj ntau cov tshuaj synthetic uas siv rau hauv ntau yam kev siv thiab tsim nyog dua rau kev ua lag luam.
Feature
(1) Kev ntshiab siab: Lemairamin tuaj yeem tau txais cov khoom ntshiab siab los ntawm kev rho tawm ntuj thiab kev ua kom huv. Kev ntshiab siab txhais tau tias muaj kev nyab xeeb zoo dua thiab muaj tsawg dua cov kev tsis zoo.
(2) Kev Nyab Xeeb: Kev nyab xeeb siab, ob peb qhov kev tsis zoo, tsis muaj kev tsis zoo pom tseeb txawm tias siv ntev.
(3) Kev Ruaj Ntseg: Lemairamin muaj kev ruaj ntseg zoo thiab tuaj yeem tswj nws cov haujlwm thiab cov txiaj ntsig nyob rau hauv ntau qhov chaw sib txawv thiab cov xwm txheej cia khoom.
(4) Yooj yim rau nqus: Lemairamin tuaj yeem nqus tau sai los ntawm lub cev tib neeg thiab faib rau ntau cov nqaij thiab cov kabmob sib txawv.
Cov ntawv thov
Lemairamin yog ib qho amide compound rho tawm los ntawm cov tawv ntoo ntawm tsob ntoo Zanthoxylum bungeanum. Tam sim no siv ua khoom noj khoom haus ntxiv, nws kuj ua haujlwm ua tus agonist ntawm alpha7 nicotinic acetylcholine receptor (α7nAChR), uas txo cov neuroinflammation hauv Alzheimer's tus kab mob, thiab yog synthetic kiag li. Wgx50 tau pom cov txiaj ntsig zoo hauv kev tshawb fawb preclinical, suav nrog kev txwv Aβ-induced neuronal apoptosis, txo cov neuronal calcium toxicity, txo cov kev sib sau ua ke ntawm Aβ oligomers hauv lub cerebral cortex, thiab txhim kho kev ua haujlwm ntawm kev paub hauv nas.
