YDL223C (HBT1) hmoov chaw tsim tshuaj paus CAS No.: 489408-02-8 99% purity min.rau cov khoom xyaw ntxiv
Khoom Parameters
| Khoom npe | HBT1 |
| Lwm lub npe | YDL 223C |
| CAS Nr. | 489408-02-8 |
| Cov mis mos molecular | C16H17F3N4O2S |
| Molecular hnyav | 386.40 Nws |
| Purity | 99.0% |
| Qhov tshwm sim | Lub teeb daj khoom |
| Ntim | 1kg rau ib lub hnab 25kg ib nruas |
| Daim ntawv thov | nootropics |
Khoom taw qhia
HBT1 khi rau ligand-binding domain ntawm α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) nyob rau hauv glutamate-dependent yam.Qhov no txhais tau hais tias HBT1 yog ib qho molecule uas tuaj yeem khi rau qhov chaw tshwj xeeb ntawm AMPA-R protein thaum muaj glutamate, thiab qhov kev khi no pab tswj cov protein ua haujlwm.AMPA receptors tau nthuav tawm thoob plaws hauv lub hauv nruab nrab lub paj hlwb thiab ua lub luag haujlwm tseem ceeb hauv kev sib txuas lus neuronal, kev hnov lus, thiab kev kawm, nco, thiab synaptic plasticity.AMPA receptors yog cov neeg txhawb nqa loj rau excitatory neurotransmission, kho kom haum sai, ceev desensitized excitation ntawm ntau synapses, thiab koom nrog cov lus teb thaum ntxov ntawm thaj tsam synaptic rau glutamate.AMPA receptors feem ntau coexpressed nrog NMDA receptors ntawm synapses, thiab ua ke lawv txhawb synaptic plasticity txheej txheem koom nrog hauv kev kawm, nco, excitotoxicity, thiab neuroprotection.
Feature
Brain-derived neurotrophic factor (BDNF) yog ib qho tseem ceeb ntawm neurotrophic uas ua lub luag haujlwm tseem ceeb hauv kev saib xyuas thiab nthuav dav ntawm cov neurons, thiab muaj zog thiab ntau yam cuam tshuam rau kev loj hlob, sib txawv, ciaj sia taus thiab tuag ntawm cov hlwb thiab cov hlwb uas tsis yog-neuronal, ua raws li ib tug neurotransmitter modulator thiab pab txhawb rau neuronal plasticity rau kev kawm thiab nco.Yog li ntawd nws yog ib qho tseem ceeb rau kev noj qab haus huv thiab kev noj qab haus huv ntawm lub paj hlwb.Kev nce hauv BDNF tuaj yeem ua pov thawj muaj txiaj ntsig zoo hauv kev kho mob thiab tiv thaiv ntau yam kab mob.
Daim ntawv thov
HBT1 yog ib qho tshiab AMPA receptor enhancer nrog qis agonism piv nrog LY451395 thiab OXP1, nws induces zus tau tej cov hlwb-derived neurotrophic yam (BDNF), thiab nws qhia me ntsis cuam tshuam nyob rau hauv thawj neurons Agitation.HBT1 khi rau ligand-binding domain ntawm AMPA-R nyob rau hauv ib tug glutamate-dependent yam.Ua ke, lawv txhawb cov txheej txheem synaptic plasticity koom nrog hauv kev kawm, nco, excitability thiab neuroprotection.Nws tuaj yeem txhim kho kev txawj ntse thiab kev nco ntawm lub hlwb, thiab txhim kho tib neeg txoj kev muaj peev xwm kawm.
