Lemairamin (WGX-50) hmoov chaw tsim tshuaj paus CAS No.: 29946-61-0 98.0% purity min. rau cov khoom xyaw ntxiv
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Khoom Parameters
| Khoom npe | Lemairamin |
| Lwm lub npe | 2-Propenamide, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-, (2E)-; Lemairamin (WGX-50) |
| CAS Nr. | 29946-61-0 |
| Cov mis mos molecular | C19H21NO3 |
| Molecular hnyav | 311.37 Nws |
| Purity | 98.0% |
| Qhov tshwm sim | Dawb mus rau dawb hmoov |
| Daim ntawv thov | Khoom noj khoom haus ntxiv Raw Khoom |
Khoom taw qhia
Lemairamin los yog Wgx50 yog ib qho khoom siv ntuj tsim tawm los ntawm cov kua txob uas tau pom tias muaj txiaj ntsig zoo hauv kev tiv thaiv kab mob Alzheimer. Cov kev tshawb fawb tau pom tias nws tuaj yeem cuam tshuam Aβ-induced neuronal apoptosis, txo cov calcium toxicity neuronal, thiab txo cov tsub zuj zuj ntawm Aβ oligomers hauv cerebral cortex. Tsis tas li ntawd, wgx50 tau pom tias txhim kho kev txawj ntse hauv nas. Kev tshawb fawb qhia tias wgx50 muaj peev xwm tiv thaiv cov protein-protein sib dhos ntawm amyloid molecules. Zuag qhia tag nrho, wgx50 muaj peev xwm tiv thaiv Alzheimer's kab mob thiab tuaj yeem muab txoj hauv kev tshiab rau kev txhim kho cov tshuaj tsom rau Aβ oligomers. Tsis tas li ntawd, WGX-50 nthuav tawm cov haujlwm tseem ceeb los tiv thaiv kev mob, uas ua rau nws muaj kev vam meej rau kev kho mob ntawm cov kab mob. WGX-50 tau pom tias muaj qhov cuam tshuam loj rau ntawm daim tawv nqaij, xws li txo qis wrinkles thiab txhim kho daim tawv nqaij elasticity. Ntxiv nrog rau cov khoom siv ntuj tsim tawm los ntawm cov nroj tsuag Zanthoxylum bungeanum, tam sim no muaj ntau cov khoom siv hluavtaws uas siv ntau yam kev siv thiab tsim nyog rau kev ua lag luam.
Feature
(1) High purity: Lemairamin tuaj yeem tau txais cov khoom siv purity siab los ntawm kev rho tawm thiab ua kom zoo dua cov txheej txheem ntau lawm. High purity txhais tau hais tias bioavailability zoo dua thiab tsawg dua qhov tsis zoo.
(2) Kev Nyab Xeeb: Kev nyab xeeb siab, tsis tshua muaj kev cuam tshuam, tsis muaj kev cuam tshuam tsis zoo txawm tias siv mus ntev.
(3) Kev ruaj ntseg: Lemairamin muaj kev ruaj ntseg zoo thiab tuaj yeem tswj hwm nws cov haujlwm thiab cov txiaj ntsig hauv qhov chaw sib txawv thiab chaw cia khoom.
(4) Yooj yim rau nqus tau: Lemairamin tuaj yeem nqus tau sai los ntawm tib neeg lub cev thiab faib rau cov ntaub so ntswg thiab kabmob sib txawv.
Daim ntawv thov
Lemairamin yog ib qho amide compound muab rho tawm los ntawm cov tawv ntoo ntawm Zanthoxylum bungeanum cog. Tam sim no siv raws li kev noj haus ntxiv, nws kuj ua tus agonist ntawm alpha7 nicotinic acetylcholine receptor (α7nAChR), uas txo cov neuroinflammation nyob rau hauv Alzheimer's kab mob, thiab yog kiag li hluavtaws.Wgx50 tau qhia txhawb cov kev tshawb fawb preclinical, nrog rau inhibiting Aβ-induced neuronal. apoptosis, txo cov neuronal calcium toxicity, txo cov tsub zuj zuj ntawm Aβ oligomers hauv cerebral cortex, thiab txhim kho kev txawj ntse hauv nas.
