RU58841 hmoov chaw tsim tshuaj CAS No.: 154992-24-2 99.0% purity min. rau cov khoom xyaw ntxiv
Cov Khoom Siv
| Lub npe khoom | 4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile |
| Lwm lub npe | RU58841 |
| CAS Nr. | 154992-24-2 |
| Cov mis molecular | C17H18F3N3O3 |
| Qhov hnyav ntawm cov molecule | 369.34 |
| Kev dawb huv | 99.0% |
| Qhov tsos | hmoov dawb |
| Ntim khoom | 1kg/lub hnab |
| Daim Ntawv Thov | Loj hlob cov plaub hau |
Kev taw qhia txog khoom
RU58841 (tseem hu ua RU-58841) yog ib qho tshuaj sib xyaw, RU58841 sib tw nrog dihydrotestosterone kom khaws cov DHT theem hauv qhov ntau thiab tsawg, yog li tswj cov plaub hau kev loj hlob voj voog. Nws txhawb kev hloov pauv ntawm cov plaub hau follicles tshiab mus rau hauv anagen plaub hau follicles los ntawm kev nkag mus rau theem anagen. Kev tso cai rau cov follicles puas tsuaj kom hloov rov qab mus rau theem kev loj hlob ib txwm pab cov hlwb rov zoo. Nws kuj tseem ua rau cov ntshav ntws mus rau cov follicles puas tsuaj thiab pab lawv rov tsim dua. Ntawm qhov tod tes, RU58841 (RU-58841) ua haujlwm los ntawm kev khi rau androgen receptors hauv cov plaub hau follicles. Yog li cov androgens tsis muaj lub sijhawm los khi thiab pib cov saw hlau ntawm androgenetic alopecia thiab pib cov txheej txheem hu ua miniaturization. Nws tau pom tias cuam tshuam cov lus poob plaub hau no hauv zos kom cov plaub hau kev loj hlob ib txwm tuaj yeem txuas ntxiv mus.
Feature
(1) Muaj peev xwm tiv thaiv kev poob plaub hau: RU58841 yog ib qho tshuaj hormones tshwj xeeb inhibitor, uas tuaj yeem tiv thaiv kev sib xyaw ua ke ntawm androgen thiab cov hlwb plaub hau ntawm lub taub hau, yog li txo qhov kev pheej hmoo ntawm kev poob plaub hau.
(2) Kev nqus tau zoo: RU58841 muaj qhov hnyav molecular me me, cov qauv yooj yim, thiab yooj yim nqus. Nws tuaj yeem nkag mus rau hauv lub cev sai sai thiab ua haujlwm hauv lub sijhawm luv luv.
(3) Kev xaiv siab rau androgen: RU58841 tuaj yeem xaiv qhov kev txwv ntawm androgen yam tsis cuam tshuam rau lwm cov tshuaj hormones.
(4) Lub sijhawm ua haujlwm ntev: RU58841 muaj lub sijhawm ntev ib nrab hauv lub cev, tuaj yeem tiv thaiv cov nyhuv ntawm androgen tas li, thiab lub sijhawm ua haujlwm tuaj yeem ntev txog 48 teev.
(5) Kev ntshiab siab: Los ntawm kev rho tawm ntuj thiab cov txheej txheem tsim khoom zoo, kev tsim kho ntawm RU58841 tuaj yeem tau txais cov khoom ntshiab siab.
Cov ntawv thov
Hauv kev tshawb fawb thiab kev sim tshuaj, RU58841 tau pom tias ua rau cov cell replication rate ntau ntxiv hauv cov stromal cell, ua rau cov cell loj hlob ntxiv hauv cov cag sab nraud thiab ua rau cov plaub hau loj hlob thiab cov plaub hau ntom ntom, yog li RU58841 yog ib qho tshuaj tshawb nrhiav rau kev kho mob androgenetic alopecia. Lub hauv paus ntsiab lus ua haujlwm tseem ceeb yog thaiv kev sib xyaw ntawm DHT thiab AR ntawm cov plaub hau follicles, uas feem ntau siv los kho cov plaub hau poob thiab cov teeb meem plaub hau poob.
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